Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,234 questions · 3,357 findings · 396 reviews

No studies found 803 · 23.9%GRADE not reported 270 · 8%Very low 757 · 22.5%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Antibiotics vs placebo

Resolution of purulent secretion · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging

Antibiotics leads to higher severity or duration of different clinical symptoms: resolution of… compared with placebo (high certainty).

1 finding from 1 review

Antibiotics vs placebo

Side effects – overall · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging

Antibiotics leads to higher side effects: total compared with placebo (high certainty).

1 finding from 1 review

Antibiotics vs placebo

Interventions side effects: diarrhoea · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging

Antibiotics leads to higher side effects: diarrhoea compared with placebo (high certainty).

1 finding from 1 review

Antibiotics vs placebo

Clinical failure · acute rhinosinusitis in adults, whether clinically diagnosed or confirmed by imaging

Antibiotics leads to lower clinical failure compared with placebo (high certainty).

1 finding from 1 review

Single herb plus conventional intervention vs conventional intervention

Visual improvement at end of treatment, as defined by two or more Snellen lines · people with diabetic retinopathy

Single herb plus conventional intervention may leads to higher visual acuity (gain of ≥ 2 lines) (end of treatment) compared with conventional intervention (low certainty).

1 finding from 1 review

Single herb plus conventional intervention vs conventional intervention

Observations in retina: reduction in haemorrhages · people with diabetic retinopathy

It is very uncertain whether single herb plus conventional intervention changes observations in retina: reduction in haemorrhages compared with conventional intervention (very low certainty).

1 finding from 1 review