Cochrane · systematic review · CD007939

Single herbal medicine for diabetic retinopathy

Zhang, HW, Zhang, H, Grant, SJ, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 3 · 50%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Single herb plus conventional intervention versus conventional intervention for diabetic retinopathy

Population: people with diabetic retinopathy
6 questions
OutcomeEffectEvidenceStatus / GRADE
Progression of retinopathy
Single herb plus conventional intervention vs conventional intervention
no estimate extractedNRNo studies
Visual acuity (gain of ≥ 2 lines) (end of treatment)
Single herb plus conventional intervention vs conventional intervention
RR 1.26 [1.08, 1.48]5 studies · 541 participantsLow
Downgraded: risk of bias, imprecision
Reduction in microaneurysms
Single herb plus conventional intervention vs conventional intervention
RR 17.9 [1.05, 305.26]1 study · 146 participantsVery low
Downgraded: risk of bias, imprecision
Observations in retina: reduction in haemorrhages
Single herb plus conventional intervention vs conventional intervention
RR 26.3 [1.59, 437.56]1 study · 146 participantsVery low
Downgraded: risk of bias, imprecision
HbA1c (%)
Single herb plus conventional intervention vs conventional intervention
no estimate extracted2 studies · 215 participantsLow
Downgraded: risk of bias, imprecision
Adverse outcomes
Single herb plus conventional intervention vs conventional intervention
no estimate extracted6 studies · 687 participantsVery low
Downgraded: risk of bias, imprecision