Findings

What do systematic reviews say?

2,256 questions · 2,339 findings · 262 reviews

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No studies found 555 · 23.7%GRADE not reported 398 · 17%Very low 572 · 24.5%Low 476 · 20.4%Moderate 240 · 10.3%High 98 · 4.2%

Continuous pulse oximetry vs no/intermittent pulse oximetry

Complications · patients undergoing surgery requiring anaesthesia

1 finding from 1 review

Pulse oximetry for perioperative monitoring 2014 · Cochrane Headline outcomes only
no estimate extracted
20802 participants
GRADE not reported

Continuous pulse oximetry vs no/intermittent pulse oximetry

In‐hospital mortality · patients undergoing surgery requiring anaesthesia

1 finding from 1 review

Pulse oximetry for perioperative monitoring 2014 · Cochrane Headline outcomes only
no estimate extracted
22021 participants
GRADE not reported

Low‐dose computed tomography (LDCT) screening vs annual chest x‐ray

Mortality: lung cancer · Patients with lung cancer

Annual low‐dose CT screening leads to lower lung cancer mortality compared with annual chest x‐ray (high certainty).

1 finding from 1 review

Screening for lung cancer 2013 · Cochrane Headline outcomes only
RR 0.8 [0.7, 0.92]
1 study · 53454 participants
High

Low‐dose computed tomography (LDCT) screening vs annual chest x‐ray

All‐cause mortality · Patients with lung cancer

Annual low‐dose CT screening showed no clear difference in all‐cause mortality compared with annual chest x‐ray (high certainty).

1 finding from 1 review

Screening for lung cancer 2013 · Cochrane Headline outcomes only
RR 0.94 [0.88, 1]
1 study · 53454 participants
High

Supported employment vs other vocational approaches

Employment ‐ obtained any job during the study (high=better) · adults with severe mental illness

It is very uncertain whether supported employment changes employment ‐ obtained any job during the study (high=better) compared with other vocational approaches (very low certainty).

1 finding from 1 review

Supported employment for adults with severe mental illness 2013 · Cochrane Headline outcomes only
RR 2.62 [2.18, 3.16]
7 studies · 951 participants
Very low

Supported employment vs other vocational approaches

Employment ‐ days in competitive employment (primary outcome) ‐ long term · adults with severe mental illness

1 finding from 1 review

Supported employment for adults with severe mental illness 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 204 participants
Very low

Supported employment vs other vocational approaches

Employment ‐ days in any form of paid employment ‐ long term · adults with severe mental illness

1 finding from 1 review

Supported employment for adults with severe mental illness 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 510 participants
Very low

Supported employment vs other vocational approaches

Employment ‐ job tenure for competitive employment (weeks) ‐ long term · adults with severe mental illness

1 finding from 1 review

Supported employment for adults with severe mental illness 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 204 participants
Very low

Supported employment vs other vocational approaches

Employment ‐ job tenure for any paid employment (weeks) ‐ long term · adults with severe mental illness

1 finding from 1 review

Supported employment for adults with severe mental illness 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 423 participants
Very low

Supported employment vs other vocational approaches

Time (days) to first competitive employment ‐ long term · adults with severe mental illness

1 finding from 1 review

Supported employment for adults with severe mental illness 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 204 participants
Very low

RDP with I-bar clasps / mesial rests vs RDP with circumferential clasps / distal rests

Change in abutment tooth mobility at 60 months · Partially edentulous patients treated with a removable dental prosthesis (RDP)

RDP with I-bar clasps / mesial rests showed no clear difference in change in abutment tooth mobility at 60 months compared with RDP with circumferential clasps / distal rests; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: partially absent dentition 2012 · Cochrane All outcomes
60 months
MD -0.01 [-0.12, 0.1]
1 study · 80 participants
GRADE not reported

Xenogeneic collagen matrix (porcine; Mucograft) vs Connective tissue autograft (palate)

Keratinised mucosa height change · Patients with implant-supported prostheses and <=1 mm keratinised mucosa

Xenogeneic collagen matrix (porcine; Mucograft) showed no clear difference in keratinised mucosa height change compared with connective tissue autograft (palate); GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: management of soft tissues for dental implants 2012 · Cochrane All outcomes
MD 0.15 [-0.72, 1.02]
1 study · 22 participants
GRADE not reported

Clobetasol propionate ointment vs 5% topical mesalazine gel in adhesive base

Pain reduction (VAS 0-10) · People with erosive oral lichen planus

Clobetasol propionate ointment 0.05% showed no clear difference in pain reduction (VAS 0-10) compared with 5% topical mesalazine gel in adhesive base; GRADE not reported.

1 finding from 1 review

Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes
MD -0.83 [-4.12, 2.46]
1 study · 12 participants
GRADE not reported

Xenogeneic collagen matrix (porcine; Mucograft) vs Connective tissue autograft (palate)

Recession (aesthetics) · Patients with implant-supported prostheses and <=1 mm keratinised mucosa

Xenogeneic collagen matrix (porcine; Mucograft) showed no clear difference in recession (aesthetics) compared with connective tissue autograft (palate); GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: management of soft tissues for dental implants 2012 · Cochrane All outcomes
MD -0.10 [-1.19, 0.99]
1 study · 22 participants
GRADE not reported

Clobetasol propionate ointment vs 5% topical mesalazine gel in adhesive base

Side effects · People with erosive oral lichen planus

1 finding from 1 review

Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes
Table 3 (Side-effects). Sardella 1998: no side-effects (there were no reported side-effects with topical mesalazine gel).
1 study · 12 participants
GRADE not reported

RDP with I-bar clasps / mesial rests vs RDP with circumferential clasps / distal rests

Treatment success rate · Partially edentulous patients treated with a removable dental prosthesis (RDP)

RDP with I-bar clasps / mesial rests showed no clear difference in treatment success (5-year) compared with RDP with circumferential clasps / distal rests; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: partially absent dentition 2012 · Cochrane All outcomes
5 years
HR 0.58 [0.25, 1.34]
1 study · 134 participants
GRADE not reported

Plain lidocaine vs buffered lidocaine

Injection site pain · Patients requiring local anaesthesia

1 finding from 1 review

Adjusting the pH of lidocaine for reducing pain on injection 2010 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 685 participants
Moderate

Plain lidocaine vs buffered lidocaine

Personal preference · Patients requiring local anaesthesia

Plain lidocaine leads to higher preference compared with buffered lidocaine (high certainty).

1 finding from 1 review

Adjusting the pH of lidocaine for reducing pain on injection 2010 · Cochrane Headline outcomes only
OR 3.01 [1.19, 4.15]
8 studies · 346 participants
High

Plain lidocaine vs buffered lidocaine

Adverse events · Patients requiring local anaesthesia

1 finding from 1 review

Adjusting the pH of lidocaine for reducing pain on injection 2010 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 182 participants
High

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Complication at augmented site · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in complication at augmented site compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant… 2009 · Cochrane All outcomes
About 4.5 months
OR 1.46 [0.26, 8.05]
1 study · 22 participants
GRADE not reported