Duration of mechanical ventilation · Mechanically ventilated adults in the intensive care unit
BIS monitoring showed no clear difference in duration of mechanical ventilation (measured in days) compared with clinical assessment (low certainty).
1 finding from 1 review
Adverse events: Measured as number of patients with adverse events · Mechanically ventilated adults in the intensive care unit
1 finding from 1 review
Death from any cause (secondary outcome 3) · Mechanically ventilated adults in the intensive care unit
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Total mortality
Beta‐blockers showed no clear difference in total mortality compared with renin‐angiotensin system inhibitors (moderate certainty).
1 finding from 1 review
Total cardiovascular disease
Beta‐blockers showed no clear difference in total cardiovascular disease compared with renin‐angiotensin system inhibitors (low certainty).
1 finding from 1 review
Stroke
Beta‐blockers probably leads to higher total stroke compared with renin‐angiotensin system inhibitors (moderate certainty).
1 finding from 1 review
Total coronary heart disease
Beta‐blockers showed no clear difference in total coronary heart disease compared with renin‐angiotensin system inhibitors (low certainty).
1 finding from 1 review
Withdrawals due to adverse events
Beta‐blockers probably leads to higher withdrawal due to adverse effect compared with renin‐angiotensin system inhibitors (moderate certainty).
1 finding from 1 review
PaO2 in mmHg (absolute values) After 24‐25 hours · pulmonary hypertension in neonates
1 finding from 1 review
Change in oxygenation index ‐ After 24 hours of treatment · pulmonary hypertension in neonates
1 finding from 1 review
All‐cause mortality · pulmonary hypertension in neonates
Sildenafil may leads to lower all‐cause mortality compared with placebo (low certainty).
1 finding from 1 review
All‐cause mortality · pulmonary hypertension in neonates
It is very uncertain whether sildenafil changes all‐cause mortality compared with active control (very low certainty).
1 finding from 1 review
All‐cause mortality · pulmonary hypertension in neonates
Sildenafil plus iNO showed no clear difference in all‐cause mortality compared with placebo plus iNO (low certainty).
1 finding from 1 review
Length of hospital stay · pulmonary hypertension in neonates
1 finding from 1 review
Intervention not reported
Systolic BP ‐ Aliskiren 75 mg vs. placebo · primary hypertension
1 finding from 1 review
Intervention not reported
Systolic BP ‐ Aliskiren 150 mg vs. placebo · primary hypertension
1 finding from 1 review
Intervention not reported
Systolic BP ‐ Aliskiren 300 mg vs. placebo · primary hypertension
1 finding from 1 review
Intervention not reported
Systolic BP ‐ Aliskiren 600 mg vs. placebo · primary hypertension
1 finding from 1 review
Intervention not reported
Diastolic BP ‐ Aliskiren 75 mg vs placebo · primary hypertension
1 finding from 1 review
Intervention not reported
Diastolic BP ‐ Aliskiren 150 mg vs placebo · primary hypertension
1 finding from 1 review