Findings

What do systematic reviews say?

4,808 questions · 8,953 findings · 827 reviews · Headline outcomes only

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No studies found 1,891 · 21.1%GRADE not reported 380 · 4.2%Very low 2,100 · 23.5%Low 2,449 · 27.4%Moderate 1,684 · 18.8%High 449 · 5%

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Antihypertensive drug therapy vs placebo

Adverse effects Range of · participants without prior cerebrovascular disease for prevention of cognitive impairment and dementia

1 finding from 1 review

Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention of… 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 16830 participants
Very low

Antihypertensive drug therapy vs placebo

Quality of life measured via Sickness Impact Profile, PGWB Positive well‐being, and EuroQoL Current Health Range of · participants without prior cerebrovascular disease for prevention of cognitive impairment and dementia

1 finding from 1 review

Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention of… 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 15795 participants
Very low

Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques

PCF · participants with chronic neuromuscular diseases

1 finding from 1 review

Cough augmentation techniques for people with chronic neuromuscular disorders 2021 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 198 participants
Very low

Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques

Any adverse events · participants with chronic neuromuscular diseases

1 finding from 1 review

Cough augmentation techniques for people with chronic neuromuscular disorders 2021 · Cochrane Headline outcomes only
no estimate extracted
64 participants
Very low

Aromatherapy plus analgesia vs placebo plus analgesia

Pain · post‐caesarean pain

2 findings from 1 review

Complementary and alternative therapies for post‐caesarean pain 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 360 participants
Low
Complementary and alternative therapies for post‐caesarean pain 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 200 participants
Low

Aromatherapy plus analgesia vs placebo plus analgesia

Anxiety (adverse effect, post‐intervention) · post‐caesarean pain

1 finding from 1 review

Complementary and alternative therapies for post‐caesarean pain 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Very low

Aromatherapy plus analgesia vs placebo plus analgesia

Heart rate · post‐caesarean pain

1 finding from 1 review

Complementary and alternative therapies for post‐caesarean pain 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Very low

Aromatherapy plus analgesia vs placebo plus analgesia

Rescue analgesic consumption · post‐caesarean pain

It is very uncertain whether aromatherapy plus analgesia changes rescue analgesic requirement compared with placebo plus analgesia (very low certainty).

1 finding from 1 review

Complementary and alternative therapies for post‐caesarean pain 2020 · Cochrane Headline outcomes only
RR 0.69 [0.19, 2.49]
3 studies · 220 participants
Very low

Aromatherapy plus analgesia vs placebo plus analgesia

Pain at six weeks after discharge · post‐caesarean pain

The review found no eligible studies for this question.

1 finding from 1 review

Complementary and alternative therapies for post‐caesarean pain 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Interpersonal Psychotherapy for Depression (IPT‐D) vs a psychoeducational intervention

Substance abuse relapse post release · drug‐using offenders with co‐occurring mental health problems

It is very uncertain whether interpersonal psychotherapy changes substance abuse relapse post release compared with a psychoeducational intervention (very low certainty).

1 finding from 1 review

Interventions for drug‐using offenders with co‐occurring mental health problems 2019 · Cochrane Headline outcomes only
RR 0.67 [0.3, 1.5]
1 study · 38 participants
Very low

Interpersonal Psychotherapy for Depression (IPT‐D) vs psychoeducational control

Relapse to drug use at 3 months · summary findings of female review

Interpersonal psychotherapy showed no clear difference in relapse to drug use at 3 months compared with psychoeducational control (low certainty).

1 finding from 1 review

Interventions for female drug‐using offenders 2019 · Cochrane Headline outcomes only
RR 0.67 [0.3, 1.5]
1 study · 38 participants
Low

CCPT vs extrapulmonary mechanical percussion

Adherence to therapy and individual preference · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 131 participants
Very low

CCPT vs ACBT

Adherence to therapy and individual preference · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

CCPT vs O‐PEP devices

Adherence to therapy and individual preference: TSS score · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 155 participants
Very low

CCPT vs AD

Adherence to therapy and individual preference · children and adolescents with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Very low

CCPT vs exercise

Adherence to therapy and individual preference · children and young adults with CF

The review found no eligible studies for this question.

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CCPT vs PEP

Adherence to therapy and individual preference · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 224 participants
Very low

Summary of findings: Comparison 3 ‐ deferiprone (DFP) vs deferoxamine

Adherence to iron chelation therapy (%, SD)

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 612 participants
Very low

DFX film‐coated tablet vs DFX dispersible tablet

Adherence to iron chelation therapy (%, SD)

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 91 participants
Very low

DFX film‐coated tablet vs DFX dispersible tablet

Sustained adherence to iron chelation therapy (%, SD)

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 54 participants
Very low