What do systematic reviews say?

Atypical vs atypical antipsychotics (only short term)

• Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 111 participants
  Moderate

Fixed dental prosthesis (cantilever FDP) vs Removable dental prosthesis (RDP)

Fixed dental prosthesis (cantilever FDP) showed no clear difference in incidence-free survival (caries, endodontic treatment, tooth loss) compared with removable dental prosthesis (RDP); GRADE not reported.

• Interventions for replacing missing teeth: partially absent dentition 2012 · Cochrane All outcomes

  3 years
  HR 0.73 [0.06, 8.41]
  1 study
  GRADE not reported

Ceramic implant abutment vs Metal implant abutments (titanium)

• Interventions for replacing missing teeth: partially absent dentition 2012 · Cochrane All outcomes
  Andersson 2003: 94% (16/17) ceramic vs 100% (12/12) titanium; Andersson 2001: 93% (28/30) ceramic vs 100% (35/35) titanium; no statistical analysis provided; no measurable / non-significant differences in alveolar bone…
  2 studies · 107 participants
  GRADE not reported

Fixed dental prosthesis (cantilever FDP) vs Removable dental prosthesis (RDP)

Fixed dental prosthesis (cantilever FDP) showed no clear difference in prosthesis survival compared with removable dental prosthesis (RDP); GRADE not reported.

• Interventions for replacing missing teeth: partially absent dentition 2012 · Cochrane All outcomes
  HR 0.59 [0.27, 1.29]
  1 study · 60 participants
  GRADE not reported

Femoral vs subclavian insertion: short‐term catheterization

Femoral showed no clear difference in immediate mechanical complications ‐ Total mechanical complications compared with subclavian insertion: short‐term catheterization (high certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 0.92 [0.56, 1.51]
  1 study · 289 participants
  High

Femoral vs subclavian insertion: short‐term catheterization

Femoral showed no clear difference in immediate mechanical complications ‐ Major mechanical complications compared with subclavian insertion: short‐term catheterization (high certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 0.5 [0.09, 2.67]
  1 study · 289 participants
  High

Femoral vs internal jugular insertion: short‐term catheterization

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter colonization compared with internal jugular insertion: short‐term catheterization (moderate certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 1.04 [0.8, 1.36]
  1 study · 637 participants
  Moderate

Femoral vs internal jugular insertion: short‐term catheterization

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter related… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 0.58 [0.14, 2.4]
  1 study · 637 participants
  Moderate

Femoral vs internal jugular insertion: short‐term catheterization

Femoral probably leads to higher catheter‐related infectious complication ‐ Subgroup Analysis for the… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 1.69 [1.08, 2.65]
  1 study · 202 participants
  Moderate

Femoral vs internal jugular insertion: short‐term catheterization

Femoral showed no clear difference in catheter‐related thrombotic complications ‐ Symptomatic deep venous… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 0.99 [0.14, 6.98]
  1 study · 736 participants
  Moderate

Femoral vs internal jugular insertion: short‐term catheterization

Femoral showed no clear difference in catheter‐related thrombotic complications ‐ Catheter related… compared with internal jugular insertion: short‐term catheterization (moderate certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 0.46 [0.21, 1.01]
  1 study · 151 participants
  Moderate

Femoral vs internal jugular insertion: short‐term catheterization

Femoral probably leads to lower immediate mechanical complications ‐ Total mechanical complications compared with internal jugular insertion: short‐term catheterization (moderate certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 0.51 [0.29, 0.88]
  1 study · 736 participants
  Moderate

Femoral vs internal jugular insertion: short‐term catheterization

Femoral showed no clear difference in immediate mechanical complications ‐ Major mechanical complications compared with internal jugular insertion: short‐term catheterization (moderate certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 0.33 [0.03, 3.16]
  1 study · 736 participants
  Moderate

Femoral vs subclavian insertion: short‐term catheterization

Femoral leads to higher catheter‐related infectious complications ‐ Catheter colonization compared with subclavian insertion: short‐term catheterization (high certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 6.43 [1.95, 21.21]
  1 study · 270 participants
  High

Femoral vs subclavian insertion: short‐term catheterization

Femoral showed no clear difference in catheter‐related infectious complications ‐ Catheter‐related… compared with subclavian insertion: short‐term catheterization (high certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 2.03 [0.19, 22.12]
  1 study · 270 participants
  High

Femoral vs subclavian insertion: short‐term catheterization

Femoral leads to higher catheter‐related thrombotic complications compared with subclavian insertion: short‐term catheterization (high certainty).

• Central venous access sites for the prevention of venous thrombosis, stenosis and infection 2012 · Cochrane Headline outcomes only
  RR 11.53 [2.8, 47.52]
  1 study · 223 participants
  High

Single‐dose vs short duration antibiotics

It is very uncertain whether single‐dose changes persistent bacteriuria compared with short‐course (3‐7 days) antibiotics (very low certainty).

• Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
  RR 1.3 [0.65, 2.62]
  2 studies · 145 participants
  Very low

Single‐dose vs short duration antibiotics

It is very uncertain whether single‐dose changes recurrence compared with short‐course (3‐7 days) antibiotics (very low certainty).

• Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
  RR 1.5 [0.43, 5.26]
  2 studies · 145 participants
  Very low

Single‐dose vs short duration antibiotics

It is very uncertain whether single‐dose changes re‐infection compared with short‐course (3‐7 days) antibiotics (very low certainty).

• Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
  RR 0.16 [0.02, 1.26]
  1 study · 45 participants
  Very low

Whole body vibration vs an active physical therapy (short‐term effects)

• Whole‐body vibration training for patients with neurodegenerative disease 2012 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 45 participants
  Low