Cochrane · systematic review · CD004084

Central venous access sites for the prevention of venous thrombosis, stenosis and infection

Ge, X, Cavallazzi, R, Li, C, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
18
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 22.2%Moderate 9 · 50%High 5 · 27.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Internal jugular versus subclavian insertion: long‐term catheterization for the prevention of venous thrombosis, stenosis and infection

Population: cancer patients
6 questions
OutcomeEffectEvidenceStatus / GRADE
Catheter‐related infectious complications ‐ Exit site infection
Internal jugular vs subclavian insertion: long‐term catheterization
RR 7 [0.88, 55.86]1 study · 200 participantsLow
Downgraded: risk of bias
Catheter‐related infectious complications ‐ Port‐related bacteraemia and/or pocket infections
Internal jugular vs subclavian insertion: long‐term catheterization
RR 0.35 [0.04, 3.32]1 study · 240 participantsModerate
Downgraded: risk of bias
Catheter‐related thrombotic complications
Internal jugular vs subclavian insertion: long‐term catheterization
RR 1.97 [0.87, 4.48]1 study · 240 participantsModerate
Downgraded: risk of bias
Immediate mechanical complications ‐ Total mechanical complications
Internal jugular vs subclavian insertion: long‐term catheterization
RR 1 [0.21, 4.84]2 studies · 468 participantsLow
Downgraded: risk of bias
Immediate mechanical complications ‐ Major mechanical complications
Internal jugular vs subclavian insertion: long‐term catheterization
RR 0.33 [0.01, 8.09]2 studies · 468 participantsLow
Downgraded: risk of bias
Late mechanical complications
Internal jugular vs subclavian insertion: long‐term catheterization
RR 1.67 [0.41, 6.79]2 studies · 468 participantsLow
Downgraded: risk of bias

Femoral versus subclavian insertion: short‐term catheterization for the prevention of venous thrombosis, stenosis and infection

Population: critically ill patients
5 questions
OutcomeEffectEvidenceStatus / GRADE
Catheter‐related infectious complications ‐ Catheter colonization
Femoral vs subclavian insertion: short‐term catheterization
RR 6.43 [1.95, 21.21]1 study · 270 participantsHigh
Catheter‐related infectious complications ‐ Catheter‐related bloodstream infection
Femoral vs subclavian insertion: short‐term catheterization
RR 2.03 [0.19, 22.12]1 study · 270 participantsHigh
Catheter‐related thrombotic complications
Femoral vs subclavian insertion: short‐term catheterization
RR 11.53 [2.8, 47.52]1 study · 223 participantsHigh
Immediate mechanical complications ‐ Total mechanical complications
Femoral vs subclavian insertion: short‐term catheterization
RR 0.92 [0.56, 1.51]1 study · 289 participantsHigh
Immediate mechanical complications ‐ Major mechanical complications
Femoral vs subclavian insertion: short‐term catheterization
RR 0.5 [0.09, 2.67]1 study · 289 participantsHigh

Femoral versus internal jugular insertion: short‐term catheterization for the prevention of venous thrombosis, stenosis and infection

Population: critically ill patients who were expected to require support with renal replacement therapy
7 questions
OutcomeEffectEvidenceStatus / GRADE
Catheter‐related infectious complications ‐ Catheter colonization
Femoral vs internal jugular insertion: short‐term catheterization
RR 1.04 [0.8, 1.36]1 study · 637 participantsModerate
Downgraded: risk of bias
Catheter‐related infectious complications ‐ Catheter related bloodstream infection
Femoral vs internal jugular insertion: short‐term catheterization
RR 0.58 [0.14, 2.4]1 study · 637 participantsModerate
Downgraded: risk of bias
Catheter‐related infectious complication ‐ Subgroup Analysis for the effect of BMI on catheter colonization ‐ Highest BMI tercile (>28.4)
Femoral vs internal jugular insertion: short‐term catheterization
RR 1.69 [1.08, 2.65]1 study · 202 participantsModerate
Downgraded: risk of bias
Catheter‐related thrombotic complications ‐ Symptomatic deep venous thrombosis
Femoral vs internal jugular insertion: short‐term catheterization
RR 0.99 [0.14, 6.98]1 study · 736 participantsModerate
Downgraded: risk of bias
Catheter‐related thrombotic complications ‐ Catheter related thrombosis
Femoral vs internal jugular insertion: short‐term catheterization
RR 0.46 [0.21, 1.01]1 study · 151 participantsModerate
Downgraded: risk of bias
Immediate mechanical complications ‐ Total mechanical complications
Femoral vs internal jugular insertion: short‐term catheterization
RR 0.51 [0.29, 0.88]1 study · 736 participantsModerate
Downgraded: risk of bias
Immediate mechanical complications ‐ Major mechanical complications
Femoral vs internal jugular insertion: short‐term catheterization
RR 0.33 [0.03, 3.16]1 study · 736 participantsModerate
Downgraded: risk of bias