Unacceptability of treatment (dropouts/exclusions during the trial) · Children and adolescents aged 16 years or less
Fluoride gel (topically applied; operator- or self-applied; any… showed no clear difference in unacceptability of treatment (dropouts/exclusions during the trial) compared with placebo or no treatment; GRADE not reported.
3 findings from 1 review
Adverse effects: dental fluorosis · general population
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Adverse effects were not reported in a usable format, but the reported rates of loose stools and diarrhoea were very similar between groups. There were no serious adverse effects during the study. Milgrom 2009.
1 study · 94 participants
GRADE not reported
Adverse events (e.g. ulcers, tooth staining) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review
Adverse effects · Children (mixed dentition; baseline about 8 years)
1 finding from 1 review
Mucosal irritation / oral soft tissue allergic reaction (signs of sensitivity) · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Caries increment (dmfs, primary and permanent teeth combined) · Children (mixed dentition; baseline about 8 years)
1 finding from 1 review
One study (252 children) compared xylitol (7.5 g/day) candy with control (sorbitol) candy over 36 months. The data could not be used in analysis because the authors combined primary/deciduous and permanent teeth and…
1 study · 252 participants
GRADE not reported
Chlorhexidine mouthrinse vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Disparities in caries across socioeconomic status (SES) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years
1 finding from 1 review
There is insufficient information to determine whether initiation of a water fluoridation programme results in a change in disparities in caries levels across SES. Data from 3 observational studies (participants not…
3 studies · 35399 participants
Low
Requirement for general anaesthesia due to dental procedures for caries · general population
The review found no eligible studies for this question.
1 finding from 1 review
Caries in primary teeth (mean number of decayed primary teeth) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Number of infants with a caries increment (dmfs) · Infants (primary teeth)
Xylitol wipes (4.2 g/day) showed no clear difference in number of infants with a caries increment (dmfs) compared with control wipes (no xylitol) (low certainty).
1 finding from 1 review
Change in proportion of caries-free children (permanent teeth) · People of all ages in a community setting; the included caries studies were all in children aged 3 to 16 years
Initiation of water fluoridation (artificial or natural) may leads to higher change in proportion of caries-free children (permanent teeth) compared with low/non-fluoridated water (0.4 ppm fluoride or less) (low certainty).
1 finding from 1 review
Dental pain due to decay · general population
The review found no eligible studies for this question.
1 finding from 1 review
Pain, quality of life, patient satisfaction or costs · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children (permanent teeth; baseline 8 to 10 years)
1 finding from 1 review
Adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, loose stool or diarrhoea) · adults
1 finding from 1 review
Patterns of adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, and loose stool or diarrhoea) were similar for both groups. Bader 2013.
1 study · 669 participants
GRADE not reported
Number of infants with a caries increment (dmfs) · Infants (primary teeth)
It is very uncertain whether xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy changes number of infants with a caries increment (dmfs) compared with control (sorbitol) tablets (very low certainty).
1 finding from 1 review
Antibiotics due to dental infections · general population
The review found no eligible studies for this question.
1 finding from 1 review
Staining · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review