Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,640 questions · 2,709 findings · 446 reviews

No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

Recurrence of pneumonia ‐ MRSA · hospital‐acquired pneumonia

Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia MRSA Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (moderate certainty).

1 finding from 1 review

Dexmedetomidine vs traditional sedative agents

Risk of delirium · Critically ill patients requiring long‐term sedation during mechanical ventilation

It is very uncertain whether dexmedetomidine changes risk of delirium compared with traditional sedative agents (very low certainty).

1 finding from 1 review

Dexmedetomidine vs traditional sedative agents

Bradycardia · Critically ill patients requiring long‐term sedation during mechanical ventilation

It is very uncertain whether dexmedetomidine changes incidence of bradycardia compared with traditional sedative agents (very low certainty).

1 finding from 1 review

Dexmedetomidine vs traditional sedative agents

All‐cause mortality · Critically ill patients requiring long‐term sedation during mechanical ventilation

It is very uncertain whether dexmedetomidine changes mortality compared with traditional sedative agents (very low certainty).

1 finding from 1 review

Silver alloyed catheter vs silicone catheter

urinary tract infections Bacterial biofilm on the surfaces of catheters. UTI was defined as uropathogenic colonisation of urinary catheter. · patients with long‐term bladder drainage in adults

Silver alloyed catheter showed no clear difference in urinary tract infections Bacterial biofilm on the surfaces of… compared with silicone catheter (low certainty).

1 finding from 1 review