Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review
AEs · chronic pain (excluding headache) in adults
no estimate extracted
0 studies · 0 participants
GRADE not reported
RR 6 [2.2, 16.4]
1 study · 140 participants
Very low
no estimate extracted
8 studies · 1314 participants
Very low
Pain intensity (Higher scores indicate higher pain intensity) · chronic pain (excluding headache) in adults
1 finding from 1 review
Participant‐reported pain relief of 30% or greater · chronic pain (excluding headache) in adults
2 findings from 1 review
Pain intensity (number of people with ≥ 50% improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review
Functional disability at 3 months ‐ not measured · chronic pain (excluding headache) in adults
2 findings from 1 review
Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review
Number experiencing adverse effects · chronic pain (excluding headache) in adults
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · chronic pain (excluding headache) in adults
1 finding from 1 review
Pain intensity (number of people with ≥ 30% improvement) (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
CBT probably leads to higher pain intensity (number of people with ≥ 30% improvement) (Higher… compared with TAU (post‐treatment) (moderate certainty).
1 finding from 1 review
Adverse events · chronic pain (excluding headache) in adults
1 finding from 1 review
Pain intensity (number of people with ≥ 50% improvement) · chronic pain (excluding headache) in adults
CBT may leads to higher pain intensity (number of people with ≥ 50% improvement) (Higher… compared with TAU (post‐treatment) (low certainty).
2 findings from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · chronic pain (excluding headache) in adults
1 finding from 1 review
Reduction in pain intensity · chronic pain (excluding headache) in adults
It is very uncertain whether CBT changes pain intensity (number of people with ≥ 30 % improvement)… compared with TAU (at follow‐up) (very low certainty).
Intervention not reported
Total studies: 42 Total participants: 14,626 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
The intervention led to lower total studies: 42 Total participants: 14,626; GRADE not reported.
1 finding from 1 review
no estimate extracted
42 participants
GRADE not reported
Intervention not reported
Desvenlafaxine high dose RCTs: 2 Participants: 870 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
1 finding from 1 review
no estimate extracted
2 participants
Very low
Intervention not reported
Total studies: 50 Total participants: 14,926 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
50 participants
GRADE not reported
Intervention not reported
Duloxetine high dose RCTs: 14 Participants: 3683 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
14 participants
Low
Intervention not reported
Duloxetine standard dose RCTs: 18 Participants: 4959 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
18 participants
Moderate
Intervention not reported
Milnacipran high dose RCTs: 2 Participants: 1670 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
2 participants
Low