Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

190 questions · 198 findings · 22 reviews · Bone, Joint and Muscle Trauma

No studies found 15 · 7.6%GRADE not reported 11 · 5.6%Very low 122 · 61.6%Low 43 · 21.7%Moderate 4 · 2%High 3 · 1.5%

Intervention not reported

Hemiarthroplasty (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with extracapsular hip fractures

It is very uncertain whether the intervention changes hemiarthroplasty (No direct evidence, indirect evidence only) (very low certainty).

1 finding from 1 review

Intervention not reported

Static fixed angle plate (5 studies; 847 participants)a · older adults (> 60 years of age) with extracapsular hip fractures

It is very uncertain whether the intervention changes static fixed angle plate (5 studies; 847 participants)a (very low certainty).

1 finding from 1 review

Intervention not reported

Long cephalomedullary nail (2 studies; 400 participants)a · older adults (> 60 years of age) with extracapsular hip fractures

It is very uncertain whether the intervention changes long cephalomedullary nail (2 studies; 400 participants)a (very low certainty).

1 finding from 1 review

Intervention not reported

Short cephalomedullary nail (33 studies; 5380 participants)a · older adults (> 60 years of age) with extracapsular hip fractures

It is very uncertain whether the intervention changes short cephalomedullary nail (33 studies; 5380 participants)a (very low certainty).

1 finding from 1 review

Intervention not reported

Hemiarthroplasty (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with extracapsular hip fractures

It is very uncertain whether the intervention changes hemiarthroplasty (No direct evidence, indirect evidence only) (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Function (all scores/instruments): intermediate term IKDC 2000 (version) score. Scale from: 0 to 100; higher scores = better function. · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes function (all scores/instruments): intermediate term IKDC 2000… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Function (all scores/instruments): long term Scale from: 0 to 100; higher scores = better function. · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes function (all scores/instruments): long term Scale from: 0 to 100;… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

QoL · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes quality of life: long‐term KOOS QOL score. Scale 0 to 100; higher… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Failure of treatment and adverse effects: long‐term Participants with surgery and symptom recurrence · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes failure of treatment and adverse effects: long‐term Participants… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Pain North Americal Spine Society pain scores. Scale from: 0 to 100 (higher scores indicate less pain). · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes pain: long‐term KOOS Pain score. Scale 0 to 100; higher scores =… compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Activity · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes activity: intermediate term (1 to 5 years compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Activity: long term (5 or more years · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes activity: long term (5 or more years compared with microfracture (very low certainty).

1 finding from 1 review

Intervention not reported

Subjective knee score ‐ KOOS‐4 score (mean score of 4 components) at 2 years: score from 0 (extreme symptoms) to 100 (no symptoms) · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
1 finding from 1 review

Intervention not reported

Treatment failure (graft rupture or ACL reconstruction) at 2 years5 · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)

The intervention may leads to lower treatment failure (graft rupture or ACL reconstruction) at 2 years5 (low certainty).

1 finding from 1 review