Systolic blood pressure > 95th percentile at 7 years · Neonates with developing BPD
Inhaled steroids showed no clear difference in systolic blood pressure > 95th percentile at 7 years compared with systemic steroids (moderate certainty).
1 finding from 1 review
BPD or death at 36 weeks' postmenstrual age№ of participants: 0 (0 RCTs) · preterm infants with respiratory distress for initial respiratory support
Inhaled steroids showed no clear difference in death or BPD at 36 weeks' postmenstrual age among all randomised compared with systemic corticosteroids (moderate certainty).
1 finding from 1 review
Intervention not reported
BPD at 28 days · Preterm neonates with respiratory distress
The intervention showed no clear difference in BPD at 28 days (low certainty).
1 finding from 1 review
Intervention not reported
Ever diagnosed as asthmatic by 7 years of age · Preterm neonates with respiratory distress
The intervention probably leads to lower ever diagnosed as asthmatic by 7 years of age (moderate certainty).
1 finding from 1 review
Death or BPD (28 days) · preterm infants with respiratory distress for initial respiratory support
Inhaled steroids showed no clear difference in death or BPD at 28 days compared with systemic corticosteroids (low certainty).
1 finding from 1 review
Bronchopulmonary dysplasia/chronic lung disease · preterm infants with respiratory distress for initial respiratory support
Inhaled steroids showed no clear difference in BPD at 36 weeks' postmenstrual age compared with systemic corticosteroids (moderate certainty).
1 finding from 1 review
BPD at 28 days · preterm infants with respiratory distress for initial respiratory support
Inhaled steroids showed no clear difference in BPD at 28 days compared with systemic corticosteroids (low certainty).
1 finding from 1 review
Intervention not reported
Duration of mechanical ventilation (days) · Preterm neonates with respiratory distress
1 finding from 1 review
Intervention not reported
Duration of supplemental oxygen (days) · Preterm neonates with respiratory distress
1 finding from 1 review
Intervention not reported
Hyperglycaemia · Preterm neonates with respiratory distress
The intervention probably leads to lower hyperglycaemia (moderate certainty).
1 finding from 1 review
Intervention not reported
Patent ductus arteriosus · Preterm neonates with respiratory distress
The intervention probably leads to higher patent ductus arteriosus (moderate certainty).
1 finding from 1 review
Intervention not reported
BPD at 36 weeks' postmenstrual age · Preterm neonates with respiratory distress
The intervention showed no clear difference in BPD at 36 weeks' postmenstrual age (moderate certainty).
1 finding from 1 review
Intervention not reported
Death from any cause prior to hospital discharge · Neonates with PPHN
The intervention showed no clear difference in death from any cause prior to hospital discharge (low certainty).
1 finding from 1 review
RR 0.2 [0.02, 1.77]
37 participants
Low
Intervention not reported
Percentage of infants that showed improvement in OI by at least 20% by the end of therapy · Neonates with PPHN
1 finding from 1 review
no estimate extracted
39 participants
Low
Intervention not reported
Adverse neurological outcomes at six months of age · Neonates with PPHN
1 finding from 1 review
no estimate extracted
37 participants
Low
Intervention not reported
Cerebral Palsy · Neonates with PPHN
1 finding from 1 review
no estimate extracted
37 participants
Low
Intervention not reported
Deafness · Neonates with PPHN
1 finding from 1 review
no estimate extracted
37 participants
Low
Intervention not reported
Need for ECMO prior to discharge · Neonates with PPHN
1 finding from 1 review
no estimate extracted
21 participants
Low
Intervention not reported
Total duration of mechanical ventilation (days) · Neonates with PPHN
The intervention showed no clear difference in total duration of mechanical ventilation (days) (low certainty).
1 finding from 1 review
no estimate extracted
37 participants
Low
Intervention not reported
Duration of iNO therapy (days) · Neonates with PPHN
1 finding from 1 review
no estimate extracted
21 participants
Low