Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

394 questions · 412 findings · 112 reviews

No studies found 51 · 12.4%GRADE not reported 41 · 10%Very low 86 · 20.9%Low 121 · 29.4%Moderate 84 · 20.4%High 29 · 7%

HFNC vs continuous positive airway pressure (CPAP)

BPD (supplemental oxygen/respiratory support at 36 weeks' postmenstrual age if born < 32 weeks' gestation, or 28 days if born ≥ 32 weeks' gestation) · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in BPD (supplemental oxygen/respiratory support at 36 weeks'… compared with continuous positive airway pressure (low certainty).

1 finding from 1 review

HFNC vs nasal intermittent positive pressure ventilation

Death (before hospital discharge) or BPD (supplemental oxygen/respiratory support at 36 weeks' postmenstrual age if born < 32 weeks' gestation, or 28 days if born ≥ 32 weeks' gestation) · preterm infants requiring primary respiratory support

It is very uncertain whether nasal high flow changes death (before hospital discharge) or BPD (supplemental… compared with nasal intermittent positive pressure ventilation (very low certainty).

1 finding from 1 review

Nasal interfaces (single nasal prong, binasal prongs (long or short), or nasal masks) vs face mask

Oxygen requirement at 36 weeks' postmenstrual age · term and preterm infants resuscitated at birth, using positive pressure ventilation

Nasal interfaces (single nasal prong, binasal prongs (long or… showed no clear difference in the need for supplemental oxygen at 36 weeks' corrected gestational… compared with face mask (low certainty).

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

Duration of any form of respiratory support (any form of non‐invasive respiratory support with or without supplemental oxygen) · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
1 finding from 1 review

Doxapram vs no treatment, placebo, methylxanthine (including theophylline, aminophylline, or caffeine), or

Chronic lung disease · treatment of apnea

The review found no eligible studies for this question.

3 findings from 1 review