Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

260 questions · 265 findings · 20 reviews · Pregnancy and Childbirth

No studies found 57 · 21.5%GRADE not reported 29 · 10.9%Very low 77 · 29.1%Low 85 · 32.1%Moderate 16 · 6%High 1 · 0.4%

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ fever (oral temperature ≥ 38°C) · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ fever (oral temperature ≥ 38°C) compared with saline placebo (moderate certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Vaginal delivery not achieved within 24 hours · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) probably leads to higher vaginal delivery not achieved within 24 hours compared with low‐dose oral misoprostol (moderate certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Uterine hyperstimulation with fetal heart rate changes · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) showed no clear difference in uterine hyperstimulation with FHR changes compared with low‐dose oral misoprostol (low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) showed no clear difference in serious neonatal morbidity or perinatal death compared with low‐dose oral misoprostol (low certainty).

1 finding from 1 review

Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid

Cure of gonococcal infection (microbiological culture) · pregnant women with gonorrhoea infection

It is very uncertain whether intramuscular ceftriaxone changes cure of gonococcal infection (microbiological culture) compared with oral amoxicillin plus oral probenecid (very low certainty).

1 finding from 1 review