Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

821 questions · 993 findings · 80 reviews · Dental caries

No studies found 60 · 6%GRADE not reported 749 · 75.4%Very low 109 · 11%Low 41 · 4.1%Moderate 34 · 3.4%High 0 · 0%

Bruxism vs No bruxism

Oral health-related quality of life · Indian children and adults

Two studies found bruxers have poorer OHRQoL than non-bruxers; narrative, ungraded.

1 finding from 1 review

Dental (tooth) agenesis vs No dental agenesis

Oral health-related quality of life · Adolescents (10-19 years)

The umbrella review reported insufficient scientific evidence to support an association between dental agenesis and oral health-related quality of life.

2 findings from 1 review

Traumatic dental injury (dental trauma) vs No dental trauma

Oral health-related quality of life · Adolescents (10-19 years)

Complicated traumatic dental injuries (pulp exposure or tooth darkening) worsen OHRQoL in adolescents, while uncomplicated injuries show little impact (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    The impact of dental trauma sequelae on OHRQoL in adolescents was observed in five systematic reviews [31-35]. The studies show that uncomplicated traumatic injuries do not have a negative impact on the OHRQoL of…
    5 studies
    GRADE not reported

Dental caries vs Caries-free controls

Oral health-related quality of life · Indians

In adolescents (10-19 years), dental caries was associated with poorer OHRQoL (pooled OR 3.92; 5 studies); ungraded.

5 findings from 1 review
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Older age vs Younger adults (population mean age <=33.4 years)

Oral health-related quality of life · Adolescents (10-19 years)

The abstract reports older age is associated with worse OHRQoL, but the body notes the evidence on age is limited and conflicting (narrative synthesis; no pooled estimate or GRADE rating).

2 findings from 1 review

Operative treatment of dental caries lesions vs No caries treatment

Oral health-related quality of life · Adolescents (10-19 years)

Operative treatment of caries lesions has a positive effect on OHRQoL in adolescents, though the included evidence was of low quality (narrative synthesis; no pooled estimate or GRADE rating by the umbrella review).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    the operative treatment of caries lesions has a positive effect on OHRQoL, despite the low quality of evidence [9]. There is low evidence that the OHRQoL of children and adolescents improved following caries…
    Studies not reported
    GRADE not reported

Periodontal disease assessed by loss of attachment (LOA / clinical attachment loss) vs Individuals without periodontal disease (by LOA)

Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)

No difference in OHRQoL was seen between groups for periodontal disease by LOA on OHIP-14/OIDP (pooled SMD -0.04, CI includes 0); ungraded.

3 findings from 1 review

Periodontal disease (severe periodontitis) vs Individuals without periodontal disease (by LOA)

Oral health-related quality of life · Adolescents (10-19 years)

Severe periodontal disease is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review

Periodontal disease assessed by Community Periodontal Index (CPI) vs Individuals without periodontal disease (by CPI)

Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)

Evidence on periodontal disease (CPI) and OHRQoL is inconsistent across studies (very low certainty).

3 findings from 1 review

Gingivitis (assessed by gingival index or WHO criteria) vs Individuals without gingivitis

Oral health-related quality of life · Indians

Continuous analyses (GOHAI, OHIP-14) of gingivitis and OHRQoL were inconsistent and mostly non-significant; ungraded.

2 findings from 1 review

Dental caries vs Absence/lower severity of dental caries

Oral health-related quality of life · Adolescents (10-19 years)

Dental caries is associated with worse OHRQoL in adolescents, with greater severity linked to greater impact (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    The impact of dental caries on OHRQoL was addressed in five systematic reviews [9, 26, 34, 36, 37]. Three articles report that the greater the severity of the carious lesion, the worse the impact on OHRQoL in…
    5 studies
    GRADE not reported

Female sex vs Male sex

Oral health-related quality of life · Adolescents (10-19 years)

The abstract reports female sex is associated with worse OHRQoL, but the conclusion states the impact of gender was not clarified (narrative synthesis; no pooled estimate or GRADE rating).

2 findings from 1 review