It is very uncertain whether oral misoprostol one‐ to two‐hourly changes oxytocin augmentation compared with oral misoprostol four‐ to six‐hourly (very low certainty).
Oral misoprostol probably leads to lower oxytocin augmentation compared with placebo/no treatment (moderate certainty).
It is very uncertain whether oral misoprostol one‐ to two‐hourly changes uterine hyperstimulation without fetal heart rate changes compared with oral misoprostol four‐ to six‐hourly (very low certainty).
Oral misoprostol 20 µg hourly titrated showed no clear difference in vaginal birth within 24 hours compared with oral misoprostol 25 µg two‐hourly static (low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes caesarean section compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation with FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes oxytocin augmentation compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation without FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes apgar score less than 7 at 5 minutes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes admission to NICU compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with placebo/no treatment (very low certainty).
It is very uncertain whether oral misoprostol changes apgar score less than 7 at 5 minutes compared with placebo/no treatment (very low certainty).
Oral misoprostol showed no clear difference in vaginal birth within 24 hours compared with vaginal dinoprostone (low certainty).
Oral misoprostol probably leads to lower caesarean section compared with vaginal dinoprostone (moderate certainty).
Amniotic membranes sweeping may leads to higher spontaneous onset of labour compared with no treatment/sham (low certainty).
Amniotic membranes sweeping showed no clear difference in spontaneous onset of labour compared with intravenous oxytocin/amniotomy (low certainty).
The review found no eligible studies for this question.