Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

313 questions · 352 findings · 23 reviews · Drugs and Alcohol

No studies found 16 · 4.5%GRADE not reported 34 · 9.7%Very low 113 · 32.1%Low 117 · 33.2%Moderate 57 · 16.2%High 15 · 4.3%

Homéogène 46/Sedatif PC (homeopathic drugs) vs placebo

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether homéogène 46/Sedatif PC (homeopathic drugs) changes benzodiazepine discontinuation, end of intervention compared with placebo (very low certainty).

1 finding from 1 review

Carbamazepine vs tricyclic antidepressants (TCAs)

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

Carbamazepine showed no clear difference in benzodiazepine discontinuation, end of intervention compared with tricyclic antidepressant (low certainty).

1 finding from 1 review

Interpersonal Psychotherapy for Depression (IPT‐D) vs Other Psychological Interventions

Substance use ‐ relapse · co‐occurring depression and substance use disorders

It is very uncertain whether interpersonal Psychotherapy for Depression (IPT‐D) changes substance use ‐ relapse compared with other Psychological Interventions (very low certainty).

1 finding from 1 review

Interpersonal Psychotherapy for Depression (IPT‐D) vs Other Psychological Interventions

Retention in treatment · co‐occurring depression and substance use disorders

It is very uncertain whether interpersonal Psychotherapy for Depression (IPT‐D) changes treatment retention compared with other Psychological Interventions (very low certainty).

1 finding from 1 review