Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

170 questions · 176 findings · 27 reviews · Acute Respiratory Infections

No studies found 11 · 6.3%GRADE not reported 31 · 17.6%Very low 18 · 10.2%Low 29 · 16.5%Moderate 67 · 38.1%High 20 · 11.4%

Intervention not reported

Incidence of adverse events ‐ co‐trimoxazole prophylaxis only · children with HIV infection aged 12 years and under

The intervention showed no clear difference in incidence of adverse events ‐ co‐trimoxazole prophylaxis only (moderate certainty).

1 finding from 1 review

Intervention not reported

Incidence of Pseudomonas infection in children with cystic fibrosis ‐ ciprofloxacin prophylaxis only · children with cystic fibrosis aged 12 years and under

The intervention showed no clear difference in incidence of Pseudomonas infection in children with cystic fibrosis… (moderate certainty).

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention led to higher treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 8 to 19 days · patients with acute otitis media

The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 20 to 30 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 8 to 19 days · patients with acute otitis media

The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 20 to 30 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 3 months or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 90 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 90 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 30 to 45 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 30 to 45 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 3 months or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review