Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

190 questions · 193 findings · 17 reviews · Headline outcomes only

No studies found 51 · 26.4%GRADE not reported 6 · 3.1%Very low 59 · 30.6%Low 55 · 28.5%Moderate 17 · 8.8%High 5 · 2.6%

Intervention not reported

Participants with at least 30% or at least 50% reduction in pain · people with cancer pain
1 finding from 1 review

Intervention not reported

PGIC much or very much improved · people with cancer pain
1 finding from 1 review

Intervention not reported

Mean pain intensity at end of study · people with cancer pain
1 finding from 1 review

Intervention not reported

Pain no worse than mild at one or two weeks (or equivalent) · people with cancer pain
1 finding from 1 review

Intervention not reported

Mean quality of life or "well‐being" · people with cancer pain
1 finding from 1 review

Intervention not reported

Participant preference · people with cancer pain
1 finding from 1 review

Intervention not reported

Serious adverse events · people with cancer pain
1 finding from 1 review

Paracetamol 500 mg to 650 mg vs placebo

Pain‐free at 1 hour · adults with episodic tension‐type headache

The review found no eligible studies for this question.

2 findings from 1 review