All‐cause mortality · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in mortality compared with prolonged‐course antibiotic therapy be used (moderate certainty).
1 finding from 1 review
Mortality NF‐GNB · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in mortality NF‐GNB compared with prolonged‐course antibiotic therapy be used (low certainty).
1 finding from 1 review
Mortality MRSA · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in mortality MRSA compared with prolonged‐course antibiotic therapy be used (moderate certainty).
1 finding from 1 review
Recurrence of pneumonia · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (low certainty).
1 finding from 1 review
Recurrence of pneumonia ‐ NF‐GNB · hospital‐acquired pneumonia
Should short‐course antibiotic therapy probably leads to higher recurrence of pneumonia NF‐GNB Clinical and/or microbiological… compared with prolonged‐course antibiotic therapy be used (moderate certainty).
1 finding from 1 review
Recurrence of pneumonia ‐ MRSA · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia MRSA Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (moderate certainty).
1 finding from 1 review
28‐day antibiotic‐free days · hospital‐acquired pneumonia
1 finding from 1 review
Duration of mechanical ventilation · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
Risk of delirium · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes risk of delirium compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Risk of coma · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes risk of coma compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Bradycardia · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes incidence of bradycardia compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Total duration of weaning defined as study randomization to successful extubation (hours) · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
Duration of ICU stay · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
All‐cause mortality · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes mortality compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Intervention not reported
Physical health: blood glucose (HbA1c) · Adult patients with long‐term health conditions
1 finding from 1 review
Intervention not reported
Physical health: systolic blood pressure · Adult patients with long‐term health conditions
1 finding from 1 review
Intervention not reported
Physical health: cholesterol (LDL‐C) · Adult patients with long‐term health conditions
1 finding from 1 review
Intervention not reported
Psychological health: depression (PHQ‐9, SCL‐20, Beck Depression Inventory, CES‐D) · Adult patients with long‐term health conditions
1 finding from 1 review
Intervention not reported
Subjective health status: condition‐specific (PAID‐2, Illness Intrusiveness, AQLQ) · Adult patients with long‐term health conditions
1 finding from 1 review
Intervention not reported
Self‐management capabilities: self efficacy (Stanford, SUPPH, PCDS) · Adult patients with long‐term health conditions
1 finding from 1 review