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What do systematic reviews say?

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Evidence found and GRADE certainty

1,655 questions · 1,751 findings · 147 reviews · Pain, Palliative and Supportive Care

No studies found 361 · 20.6%GRADE not reported 87 · 5%Very low 625 · 35.7%Low 367 · 21%Moderate 232 · 13.2%High 79 · 4.5%

Intervention not reported

"Substantial" benefit At least 50% reduction in pain or equivalent · adults with neuropathic pain (Trigeminal neuralgia, painful diabetic neuropathy, chronic post stroke pain)

The intervention may leads to higher "Substantial" benefit At least 50% reduction in pain or equivalent (low certainty).

1 finding from 1 review

Intervention not reported

"Moderate" benefit At least 30% reduction in pain · adults with neuropathic pain (Trigeminal neuralgia, painful diabetic neuropathy, chronic post stroke pain)
1 finding from 1 review

Intervention not reported

Proportion below 30/100 mm on VAS · adults with neuropathic pain (Trigeminal neuralgia, painful diabetic neuropathy, chronic post stroke pain)
1 finding from 1 review

Intervention not reported

Patient Global Impression of Change much or very much improved · adults with neuropathic pain (Trigeminal neuralgia, painful diabetic neuropathy, chronic post stroke pain)
1 finding from 1 review

Intervention not reported

Any adverse event · adults with neuropathic pain (Trigeminal neuralgia, painful diabetic neuropathy, chronic post stroke pain)

The intervention may leads to higher any adverse event (low certainty).

1 finding from 1 review

Intervention not reported

Adverse event withdrawals · adults with neuropathic pain (Trigeminal neuralgia, painful diabetic neuropathy, chronic post stroke pain)
1 finding from 1 review

Intervention not reported

Serious adverse events · adults with neuropathic pain (Trigeminal neuralgia, painful diabetic neuropathy, chronic post stroke pain)
1 finding from 1 review

Intervention not reported

"Moderate" benefit At least 30% reduction in pain · Adults with cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Patient Global Impression of Change much or very much improved · Adults with cancer pain

The review found no eligible studies for this question.

1 finding from 1 review