Cochrane · systematic review · CD007403
Salicylate‐containing rubefacients for acute and chronic musculoskeletal pain in adults
Derry, S, Matthews, PRL, Wiffen, PJ, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 83.3%Low 1 · 16.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adults with strains or sprains (acute) or osteoarthritis or low back pain (chronic)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical success (eg 50% reduction in pain) Acute conditions | no estimate extracted | 4 studies · 324 participants | Very low |
Clinical success (eg 50% reduction in pain) Chronic conditions | no estimate extracted | 6 studies · 455 participants | Very low |
Adverse events ‐ any adverse events Acute and chronic conditions combined | no estimate extracted | 11 studies · 984 participants | Low |
Adverse events ‐ local adverse events Acute and chronic conditions combined | no estimate extracted | 10 studies · 869 participants | Very low |
Withdrawals ‐ lack of efficacy Acute and chronic conditions combined | no estimate extracted | 5 studies · 501 participants | Very low |
Withdrawals ‐ adverse events Acute and chronic conditions combined | no estimate extracted | 7 studies · 737 participants | Very low |