Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,097 questions · 3,266 findings · 631 reviews

No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

High‐grade cervical, vulval, vaginal, penile, or anal intraepithelial neoplasia · 9‐ to 14‐year‐old females and males

The review found no eligible studies for this question.

1 finding from 1 review

Nonavalent HPV vaccine vs quadrivalent HPV vaccine

High‐grade cervical intraepithelial neoplasia, adenocarcinoma in situ, and cervical cancer · 9‐ to 26‐year‐old females and males

Nonavalent HPV vaccine showed no clear difference in high‐grade cervical intraepithelial neoplasia, adenocarcinoma in… compared with quadrivalent HPV vaccine (high certainty).

1 finding from 1 review

Nonavalent HPV vaccine vs quadrivalent HPV vaccine

High‐grade cervical, vulval, and vaginal disease · 9‐ to 26‐year‐old females and males

Nonavalent HPV vaccine showed no clear difference in high‐grade cervical, vulval, and vaginal disease at up to 4.5‐year compared with quadrivalent HPV vaccine (high certainty).

1 finding from 1 review

Exercise vs no exercise

Hand function ‐ short term (less than 3 months) Grip function test scale of 0 to 80 points (higher score indicates better grip function) · rheumatoid arthritis of the hand
1 finding from 1 review

Exercise vs no exercise

Hand function ‐ long term (12 months and beyond) Overall hand function subscale of the Michigan Hand Questionnaire, 0 to 100 (higher scores mean better hand function) · rheumatoid arthritis of the hand
2 findings from 1 review