Serious adverse events · people with active UC
It is very uncertain whether antibiotics plus probiotics changes serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with active UC
It is very uncertain whether antibiotics plus probiotics changes withdrawals due to adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Failure to induce clinical remission at end of study · people with active UC
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient discomfort during treatment (anxiety scale) · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
One study found no significant difference in patient discomfort between SDF and ART (p = 0.15; ungraded).
1 finding from 1 review
Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
SDF was not significantly better than ART at arresting caries (pooled ES 0.05, 95% CI -0.42 to 0.51; ungraded).
1 finding from 1 review
Diabetic complications · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects of treatment · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
1 finding from 1 review
Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
A single (one-time) SDF application did not significantly arrest caries (pooled ES -0.09, 95% CI -0.48 to 0.29; ungraded).
1 finding from 1 review
Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
The pooled caries arrest rate with SDF (>=30%, applied annually/biannually) was 51.62% (622/1205 lesions arrested) at >=12 months follow-up.
1 finding from 1 review
Resource implications (e.g. cost of incontinence management methods) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
The review found no eligible studies for this question.
1 finding from 1 review
Included studies did not report cost data. A brief economic commentary drew on four external economic evaluations (Smits 2020, Nasseh 2017, Choi 2020, Soloweij-Wedderburn 2017) suggesting potential cost…
0 studies
No studies found
Clinical attachment level (CAL) · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
Periodontal treatment (subgingival instrumentation, with or without… led to lower clinical attachment level (CAL) compared with no active intervention/usual care; GRADE not reported.
1 finding from 1 review
MD -0.48 [-0.65, -0.31]
18 studies
GRADE not reported
Size of the lower jaw (arch length, change) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Schwarz appliance showed no clear difference in size of the lower jaw (mandibular arch length, change) at 9 months compared with no active treatment (control); GRADE not reported.
1 finding from 1 review
Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
1 finding from 1 review
Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
It is very uncertain whether lower lip bumper changes amount of crowding (change in mandibular incisor crowding) at 6 months compared with no active treatment (control) (very low certainty).
1 finding from 1 review
Lower incisors to mandible (position, mm) at 9 months · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Lower lip bumper led to higher lower incisors to mandible at 6 months compared with no active treatment (control); GRADE not reported.
1 finding from 1 review
Size of the lower jaw (arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Lower lip bumper led to higher size of the lower jaw (mandibular arch length) at 6 months compared with no active treatment (control); GRADE not reported.
1 finding from 1 review
Amount of crowding (change in mandibular crowding) at 8 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
It is very uncertain whether schwarz appliance changes amount of crowding (lower arch crowding, change) at 9 months compared with no active treatment (control) (very low certainty).
1 finding from 1 review
Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
It is very uncertain whether extraction of third molars (wisdom teeth) changes amount of crowding (Little's Irregularity Index, change) at 5 years compared with no active treatment (control) (very low certainty).
1 finding from 1 review
Size of the lower jaw (arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
Lower lingual arch led to higher size of the lower jaw (mandibular arch length) at 1 year compared with no active treatment (control); GRADE not reported.
1 finding from 1 review