Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,539 questions · 2,602 findings · 424 reviews · Headline outcomes only

No studies found 572 · 22%GRADE not reported 189 · 7.3%Very low 527 · 20.3%Low 685 · 26.3%Moderate 514 · 19.8%High 115 · 4.4%

Pharmacological interventions vs placebo

Acceptability · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: post‐intervention compared with placebo (very low certainty).

2 findings from 1 review

Psychological interventions vs treatment

Incidence of depression ‐ short term: < 6 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether psychological interventions changes incidence of depression ‐ short term: < 6 months compared with treatment (very low certainty).

1 finding from 1 review

Psychological interventions vs treatment

Acceptability · adults with long‐term physical conditions (18 years or older)

Psychological interventions may leads to higher acceptability ‐ drop‐outs due to any cause: post‐intervention compared with treatment (low certainty).

2 findings from 1 review

Pharmacological interventions vs placebo

Incidence of depression ‐ post‐intervention: 0 months · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes incidence of depression ‐ post‐intervention: 0 months compared with placebo (very low certainty).

1 finding from 1 review