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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,558 questions in 115 reviews · Vascular

current versions
No studies 346 · 22.2%Ungraded 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Ultrasound guidance vs landmark method
Patient satisfaction NRS from 0 to 10 or 4‐step Likert scale The higher the score, the higher the level of satisfaction · adults undergoing peripheral venous cannulation classed as easya
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extractedNRNo studies
Ultrasound guidance vs landmark method
Overall complications · adults undergoing peripheral venous cannulation classed as easya
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
RR 2.48 [0.9, 6.87]1 study · 596 participantsModerate
Ultrasound guidance vs landmark method
Pain NRS: from 0 to 10, where 10 is maximum pain · adults undergoing peripheral venous cannulation classed as difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extracted4 studies · 323 participantsVery low
Ultrasound guidance vs landmark method
Procedure time for first‐pass cannulation (seconds) · adults undergoing peripheral venous cannulation classed as difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extracted2 studies · 219 participantsLow
Ultrasound guidance vs landmark method
Number of cannulation attempts · adults undergoing peripheral venous cannulation classed as difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extracted9 studies · 568 participantsVery low
Ultrasound guidance vs landmark method
Patient satisfaction NRS from 0 to 10 or 4‐step Likert scale The higher the score, the higher the level of satisfaction · adults undergoing peripheral venous cannulation classed as difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extracted5 studies · 333 participantsVery low
Ultrasound guidance vs landmark method
Overall complications · adults undergoing peripheral venous cannulation classed as difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
RR 0.64 [0.37, 1.1]5 studies · 431 participantsLow
Ultrasound guidance vs landmark method
First‐pass success of cannulation · adults undergoing peripheral venous cannulation classed as moderately difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
RR 1.14 [1.02, 1.27]1 study · 401 participantsModerate
Ultrasound guidance vs landmark method
Overall success of cannulation · adults undergoing peripheral venous cannulation classed as moderately difficulta
Ultrasound guidance versus landmark method for peripheral venous cannulation in adults (2022) · Cochrane
no estimate extractedNRNo studies
Ultrasound‐accelerated thrombolysis vs thrombolysis alone
Primary patency · adults with ALI
Percutaneous thrombectomy or ultrasound‐accelerated thrombolysis for initial management of acute limb… (2022) · Cochrane
no estimate extracted1 study · 60 participantsUngraded
Ultrasound‐accelerated thrombolysis vs thrombolysis alone
Amputation rate · adults with ALI
Percutaneous thrombectomy or ultrasound‐accelerated thrombolysis for initial management of acute limb… (2022) · Cochrane
RR 1.14 [0.17, 7.59]1 study · 60 participantsVery low
Ultrasound‐accelerated thrombolysis vs thrombolysis alone
Major bleeding · adults with ALI
Percutaneous thrombectomy or ultrasound‐accelerated thrombolysis for initial management of acute limb… (2022) · Cochrane
RR 1.71 [0.31, 9.53]1 study · 60 participantsVery low
Ultrasound‐accelerated thrombolysis vs thrombolysis alone
Clinical success ‐ increase in ABI by at least 0.2 · adults with ALI
Percutaneous thrombectomy or ultrasound‐accelerated thrombolysis for initial management of acute limb… (2022) · Cochrane
RR 1 [0.94, 1.07]1 study · 60 participantsVery low
Ultrasound‐accelerated thrombolysis vs thrombolysis alone
Secondary patency · adults with ALI
Percutaneous thrombectomy or ultrasound‐accelerated thrombolysis for initial management of acute limb… (2022) · Cochrane
no estimate extracted1 study · 60 participantsUngraded
Ultrasound‐accelerated thrombolysis vs thrombolysis alone
Adverse events · adults with ALI
Percutaneous thrombectomy or ultrasound‐accelerated thrombolysis for initial management of acute limb… (2022) · Cochrane
RR 5.69 [0.28, 113.72]1 study · 60 participantsVery low
Higher‐dose heparin vs standard‐dose heparin
VTE · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.55 [0.05, 5.99]4 studies · 597 participantsLow
Heparin vs pentasaccharide
All‐cause mortality · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted1 study · 198 participantsVery low
Heparin vs pentasaccharide
VTE‐related mortality · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted1 study · 198 participantsVery low
Heparin vs pentasaccharide
PE · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted1 study · 198 participantsVery low
Heparin vs pentasaccharide
DVT · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.83 [0.19, 3.61]1 study · 175 participantsLow
Heparin vs pentasaccharide
Adverse events (thrombocytopenia) · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.34 [0.01, 8.25]1 study · 198 participantsVery low
Heparin started before vs after the surgical procedure
VTE · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.11 [0.01, 2.01]1 study · 100 participantsLow
Heparin started before vs after the surgical procedure
Major bleeding · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 3 [0.13, 71.92]1 study · 100 participantsVery low
Heparin started before vs after the surgical procedure
All‐cause mortality · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted1 study · 100 participantsVery low
Heparin started before vs after the surgical procedure
VTE‐related mortality · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted1 study · 100 participantsVery low
Heparin started before vs after the surgical procedure
PE · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extractedNRNo studies
Higher‐dose heparin vs standard‐dose heparin
Major bleeding · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 1.19 [0.48, 2.96]4 studies · 597 participantsLow
Heparin started before vs after the surgical procedure
DVT · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.11 [0.01, 2.01]1 study · 100 participantsLow
Heparin started before vs after the surgical procedure
Adverse events (thrombocytopenia) · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extractedNRNo studies
Combined mechanical and pharmacological prophylaxis vs mechanical prophylaxis alone
VTE · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.05 [0, 0.89]1 study · 150 participantsLow
Combined mechanical and pharmacological prophylaxis vs mechanical prophylaxis alone
Major bleeding · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted1 study · 150 participantsLow
Combined mechanical and pharmacological prophylaxis vs mechanical prophylaxis alone
All‐cause mortality · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted1 study · 150 participantsLow
Combined mechanical and pharmacological prophylaxis vs mechanical prophylaxis alone
VTE‐related mortality · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted1 study · 150 participantsLow
Combined mechanical and pharmacological prophylaxis vs mechanical prophylaxis alone
PE · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extractedNRNo studies
Combined mechanical and pharmacological prophylaxis vs mechanical prophylaxis alone
DVT · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.05 [0, 0.89]1 study · 150 participantsLow
Combined mechanical and pharmacological prophylaxis vs mechanical prophylaxis alone
Adverse events · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extractedNRNo studies
Higher‐dose heparin vs standard‐dose heparin
All‐cause mortality · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted4 studies · 597 participantsLow
Higher‐dose heparin vs standard‐dose heparin
VTE‐related mortality · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
no estimate extracted4 studies · 597 participantsLow
Higher‐dose heparin vs standard‐dose heparin
PE · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.37 [0.02, 8.92]2 studies · 310 participantsVery low
Higher‐dose heparin vs standard‐dose heparin
DVT · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 1.1 [0.07, 17.4]4 studies · 597 participantsVery low
Higher‐dose heparin vs standard‐dose heparin
Adverse events (thrombocytopenia) · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 1.1 [0.07, 17.4]2 studies · 310 participantsVery low
Heparin vs pentasaccharide
VTE · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 0.83 [0.19, 3.61]1 study · 175 participantsLow
Heparin vs pentasaccharide
Major bleeding · people undergoing bariatric surgery
Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery (2022) · Cochrane
RR 1.7 [0.42, 6.92]1 study · 198 participantsVery low
Intra‐arterial delivery vs intravenous delivery
30‐Day amputation‐free survival · patients with < 30 days' limb ischaemiaa
Infusion techniques for peripheral arterial thrombolysis (2021) · Cochrane
OR 1.71 [0.4, 7.34]1 study · 40 participantsVery low
High‐dose vs low‐dose regimens of thrombolytic agents
30‐Day mortality · patients with < 42 days' limb ischaemiaa
Infusion techniques for peripheral arterial thrombolysis (2021) · Cochrane
no estimate extracted4 studies · 302 participantsVery low
High‐dose vs low‐dose regimens of thrombolytic agents
Vessel patency (at end of treatment) · patients with < 42 days' limb ischaemiaa
Infusion techniques for peripheral arterial thrombolysis (2021) · Cochrane
no estimate extracted4 studies · 302 participantsVery low
High‐dose vs low‐dose regimens of thrombolytic agents
Duration of thrombolysis (to end of treatment) · patients with < 42 days' limb ischaemiaa
Infusion techniques for peripheral arterial thrombolysis (2021) · Cochrane
no estimate extracted4 studies · 302 participantsVery low
High‐dose vs low‐dose regimens of thrombolytic agents
CVA ( · patients with < 42 days' limb ischaemiaa
Infusion techniques for peripheral arterial thrombolysis (2021) · Cochrane
no estimate extracted4 studies · 302 participantsVery low
High‐dose vs low‐dose regimens of thrombolytic agents
Major bleeding ( · patients with < 42 days' limb ischaemiaa
Infusion techniques for peripheral arterial thrombolysis (2021) · Cochrane
no estimate extracted4 studies · 302 participantsVery low
Continuous infusion vs forced (or pulse) infusion of thrombolytic agents
30‐Day amputation‐free survival · patients with less than 42 days' lower limb ischaemiaa
Infusion techniques for peripheral arterial thrombolysis (2021) · Cochrane
no estimate extracted4 studies · 304 participantsVery low