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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

430 questions in 68 reviews · Tobacco Addiction

current versions
No studies 26 · 6%Ungraded 12 · 2.8%Very low 116 · 27%Low 159 · 37%Moderate 87 · 20.2%High 30 · 7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Behavioural interventions vs minimal control
Computer‐based interventions vs control Smoking cessation · young people
Tobacco cessation interventions for young people (2017) · Cochrane
RR 0.79 [0.5, 1.24]3 studies · 340 participantsLow
Behavioural interventions vs minimal control
Text messaging‐based interventions vs control Smoking cessation · young people
Tobacco cessation interventions for young people (2017) · Cochrane
RR 1.18 [0.9, 1.56]3 studies · 2985 participantsLow
Behavioural interventions vs minimal control
Interventions with multiple delivery methods vs control Smoking cessation · young people
Tobacco cessation interventions for young people (2017) · Cochrane
RR 1.26 [0.95, 1.66]8 studies · 2755 participantsVery low
Pharmacological interventions vs placebo
Comparisons and outcomes · young people
Tobacco cessation interventions for young people (2017) · Cochrane
no estimate extractedNRNo studies
Pharmacological interventions vs placebo
NRT vs placebo Smoking cessation · young people
Tobacco cessation interventions for young people (2017) · Cochrane
RR 1.11 [0.48, 2.58]2 studies · 385 participantsVery low
Pharmacological interventions vs placebo
NRT vs placebo Adverse events · young people
Tobacco cessation interventions for young people (2017) · Cochrane
no estimate extracted2 studies · 385 participantsVery low
Interventions directed at individuals: full financial coverage vs no financial coverage
Abstinence from smoking · smokers
Healthcare financing systems for increasing the use of tobacco dependence treatment (2017) · Cochrane
RR 1.77 [1.37, 2.28]6 studies · 9333 participantsModerate
Interventions directed at healthcare providers vs placebo
Abstinence from smoking · physicians and clinics from a multispecialty group practice
Healthcare financing systems for increasing the use of tobacco dependence treatment (2017) · Cochrane
RR 1.16 [0.98, 1.37]2 studies · 2311 participantsModerate
Intervention NR
Smoking prevalence ( · Adults who smoke
Mass media interventions for smoking cessation in adults (2017) · Cochrane
no estimate extractedNRVery low
Intervention NR
Tobacco consumption ( · Adults who smoke
Mass media interventions for smoking cessation in adults (2017) · Cochrane
no estimate extractedNRVery low
Intervention NR
Abstinence or quit rates ( · Adults who smoke
Mass media interventions for smoking cessation in adults (2017) · Cochrane
no estimate extractedNRVery low
Intervention NR
Quit attempts ( · Adults who smoke
Mass media interventions for smoking cessation in adults (2017) · Cochrane
no estimate extractedNRVery low
Intervention NR
Outcomes1 · adults who want to stop smoking
Internet‐based interventions for smoking cessation (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Interactive and tailored versus non‐active control Self‐report or bio‐verified smoking cessation · adults who want to stop smoking
Internet‐based interventions for smoking cessation (2017) · Cochrane
RR 1.15 [1.01, 1.3]8 studies · 6786 participantsLow
Intervention NR
Internet versus active control Self‐report or bio‐verified smoking cessation · adults who want to stop smoking
Internet‐based interventions for smoking cessation (2017) · Cochrane
RR 0.92 [0.78, 1.09]5 studies · 3806 participantsModerate
Intervention NR
Internet plus behavioural support versus non‐Internet‐based non‐active control Self‐report or bio‐verified smoking cessation · adults who want to stop smoking
Internet‐based interventions for smoking cessation (2017) · Cochrane
RR 1.69 [1.3, 2.18]5 studies · 2334 participantsModerate
Intervention NR
Internet plus behavioural support versus non‐Internet‐based active control Self‐report or bio‐verified smoking cessation · adults who want to stop smoking
Internet‐based interventions for smoking cessation (2017) · Cochrane
RR 1 [0.84, 1.18]4 studies · 2769 participantsModerate
Intervention NR
Comparisons between Internet interventions (programmes): tailored/interactive versus not tailored/interactive Self‐report or bio‐verified smoking cessation · adults who want to stop smoking
Internet‐based interventions for smoking cessation (2017) · Cochrane
RR 1.1 [0.99, 1.22]7 studies · 14623 participantsModerate
Intervention NR
Comparisons between Internet interventions (messages): tailored/interactive versus not tailored/interactive Self‐reported smoking cessation · adults who want to stop smoking
Internet‐based interventions for smoking cessation (2017) · Cochrane
RR 1.17 [0.97, 1.41]3 studies · 4040 participantsLow
Intervention NR
Smoking uptake at longest · Children and adolescents aged 5 ‐ 18 years who were non‐smokers at baseline
Incentives for preventing smoking in children and adolescents (2017) · Cochrane
RR 1 [0.84, 1.19]3 studies · 3056 participantsLow
Intervention NR
Smoking uptake at longest · Children and adolescents aged 5 ‐ 18 years who were non‐smokers at baseline
Incentives for preventing smoking in children and adolescents (2017) · Cochrane
RR 0.82 [0.63, 1.08]3 studies · 4219 participantsVery low
Intervention NR
Cessation outcome Self‐reported/verified abstinence · Smokers
System change interventions for smoking cessation (2017) · Cochrane
no estimate extracted4 studies · 7142 participantsVery low
Intervention NR
Provision of cessation counselling Proportion of smokers counselled to quit · Smokers
System change interventions for smoking cessation (2017) · Cochrane
no estimate extracted4 studies · 10949 participantsLow
Intervention NR
Asking about tobacco use Proportion of smokers asked about tobacco use · Smokers
System change interventions for smoking cessation (2017) · Cochrane
no estimate extracted3 studies · 2615 participantsLow
Intervention NR
Provision of cessation advice Proportion of smokers advised to quit · Smokers
System change interventions for smoking cessation (2017) · Cochrane
no estimate extracted3 studies · 3003 participantsLow
Intervention NR
Quitline referral Proportion of smokers referred to quitline · Smokers
System change interventions for smoking cessation (2017) · Cochrane
no estimate extracted3 studies · 3006 participantsVery low
Intervention NR
Quitline enrolment Proportion of smokers enrolled in quitline · Smokers
System change interventions for smoking cessation (2017) · Cochrane
no estimate extracted2 studies · 1191 participantsVery low
Intervention NR
Prescription of NRT or other pharmacotherapy Proportion of smokers received NRT prescription · Smokers
System change interventions for smoking cessation (2017) · Cochrane
no estimate extracted2 studies · 2615 participantsLow
Intervention NR
Prevalence of tobacco use · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes.
Tobacco packaging design for reducing tobacco use (2017) · Cochrane
no estimate extracted1 study · 7e+05 participantsLow
Intervention NR
Change in tobacco consumption among smokers · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes.
Tobacco packaging design for reducing tobacco use (2017) · Cochrane
no estimate extracted4 studies · 9394 participantsVery low
Intervention NR
Attempts to quit smoking · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes.
Tobacco packaging design for reducing tobacco use (2017) · Cochrane
no estimate extracted2 studies · 5441 participantsLow
Intervention NR
Uptake ‐ not measured · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes.
Tobacco packaging design for reducing tobacco use (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Relapse ‐ not measured · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes.
Tobacco packaging design for reducing tobacco use (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cessation ‐ not measured · General population for prevalence outcomes. Adult smokers for tobacco consumption outcomes.
Tobacco packaging design for reducing tobacco use (2017) · Cochrane
no estimate extractedNRNo studies
Active NRT vs placebo ‐ rs1051730 ‐ non‐Hispanic white
Abstinence at end of treatment · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.63 [1.14, 2.32]2 studies · 1391 participantsModerate
Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American
Abstinence at 6 months ‐ homozygous major · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.47 [1.07, 2.03]2 studies · 637 participantsHigh
Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American
Abstinence at 6 months ‐ heterozygous or homozygous minor · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 0.43 [0.15, 1.26]2 studies · 72 participantsLow
Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American
Abstinence at end of treatment · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.03 [0.36, 2.94]2 studies · 709 participantsModerate
Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American
Abstinence at end of treatment ‐ homozygous major · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.57 [1.15, 2.15]2 studies · 637 participantsHigh
Active NRT vs placebo ‐ rs16969968 ‐ non‐Hispanic black or African American
Abstinence at end of treatment ‐ heterozygous or homozygous minor · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 0.29 [0.1, 0.86]2 studies · 72 participantsModerate
Active NRT vs placebo ‐ rs 588765 ‐ non‐Hispanic white
End of treatment · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.33 [1.04, 1.71]2 studies · 923 participantsModerate
Active NRT vs placebo ‐ rs 588765 ‐ non‐Hispanic white
End of treatment ‐ homozygous major · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.39 [0.89, 2.16]2 studies · 296 participantsLow
Active NRT vs placebo ‐ rs 588765 ‐ non‐Hispanic white
End of treatment ‐ heterozygous · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.27 [0.89, 1.79]2 studies · 469 participantsLow
Active NRT vs placebo ‐ rs 588765 ‐ non‐Hispanic white
End of treatment ‐ homozygous minor · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.5 [0.74, 3.06]2 studies · 158 participantsLow
Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American
6‐Month abstinence · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.18 [0.75, 1.87]2 studies · 708 participantsLow
Active NRT vs placebo ‐ rs1051730 ‐ non‐Hispanic white
Abstinence at end of treatment ‐ homozygous major · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.09 [0.85, 1.41]2 studies · 582 participantsLow
Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American
6‐Month abstinence ‐ homozygous major · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.95 [0.46, 8.26]2 studies · 425 participantsVery low
Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American
6‐Month abstinence ‐ heterozygous or homozygous minor · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 0.9 [0.4, 2.03]2 studies · 283 participantsModerate
Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American
End of treatment · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 1.22 [0.77, 1.93]2 studies · 708 participantsLow
Active NRT vs placebo ‐ rs2036527 ‐ non‐Hispanic black or African American
End of treatment ‐ homozygous major · people who smoke
Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers (2017) · Cochrane
RR 2.39 [0.43, 13.35]2 studies · 425 participantsLow