Subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L or less) · general population over 2 years of age
Staple foods fortified with vitamin A plus other micronutrients probably leads to lower subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L… compared with same unfortified staple foods (moderate certainty).
1 finding from 1 review
Clinical vitamin A deficiency (as defined by night blindness) · general population over 2 years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression to late AMD (neovascular AMD, geographic atrophy or both) · people with AMD
It is very uncertain whether vitamin E changes progression to late AMD (neovascular AMD, geographic atrophy or both) compared with placebo (very low certainty).
1 finding from 1 review
Progression to neovascular AMD · people with AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression to geographic atrophy · people with AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with AMD
Vitamin E showed no clear difference in progression to visual loss (loss of 3 or more lines on logMAR chart) compared with placebo (low certainty).
1 finding from 1 review
Quality of life · people with AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · people with AMD
It is very uncertain whether vitamin E changes adverse effects compared with placebo (very low certainty).
1 finding from 1 review
no estimate extracted
4 participants
Very low
Resource use and costs · people with AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to resolution of acute illness · children with acute pneumonia
1 finding from 1 review
Number of days in hospital (duration of hospitalisation) · children with acute pneumonia
1 finding from 1 review
Mortality rate ( · children with acute pneumonia
Vitamin D showed no clear difference in mortality rate ( compared with placebo (low certainty).
1 finding from 1 review
Quality of life · premenopausal women (age 18–32.7 years)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Vertebral fracture · premenopausal women (age 18–32.7 years)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐vertebral fractures · premenopausal women (age 18–32.7 years)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acceptability: total withdrawals · premenopausal women (age 18–32.7 years)
Vitamin D showed no clear difference in withdrawals from the study for any reason compared with placebo (moderate certainty).
1 finding from 1 review
Serious adverse events · premenopausal women (age 18–32.7 years)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Total hip BMD · premenopausal women (age 18–32.7 years)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Lumbar spine bone mineral density (BMD) · premenopausal women (age 18–32.7 years)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · people with chronic liver diseases
It is very uncertain whether vitamin D changes all‐cause mortality compared with placebo or no intervention (very low certainty).
1 finding from 1 review