Cochrane · systematic review · CD011597

Vitamin D as an adjunct to antibiotics for the treatment of acute childhood pneumonia

Das, RR, Singh, M, Naik, SS · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Acute Respiratory Infections2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Vitamin D compared with placebo for acute childhood pneumonia

Population: children with acute pneumonia
3 questions
OutcomeEffectEvidenceStatus / GRADE
Time to resolution of acute illness (
Vitamin D vs placebo
no estimate extracted5 studies · 1188 participantsModerate
Downgraded: indirectness
Duration of hospitalisation (
Vitamin D vs placebo
no estimate extracted5 studies · 1023 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Mortality rate (
Vitamin D vs placebo
RR 0.69 [0.44, 1.07]3 studies · 584 participantsLow
Downgraded: imprecision, indirectness