Cochrane · systematic review · CD011597
Vitamin D as an adjunct to antibiotics for the treatment of acute childhood pneumonia
Das, RR, Singh, M, Naik, SS · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyVitamin D compared with placebo for acute childhood pneumonia
Population: children with acute pneumonia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to resolution of acute illness ( Vitamin D vs placebo | no estimate extracted | 5 studies · 1188 participants | Moderate Downgraded: indirectness |
Duration of hospitalisation ( Vitamin D vs placebo | no estimate extracted | 5 studies · 1023 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Mortality rate ( Vitamin D vs placebo | RR 0.69 [0.44, 1.07] | 3 studies · 584 participants | Low Downgraded: imprecision, indirectness |
Vitamin D compared with placebo for acute childhood pneumonia
Population: children with acute pneumonia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to resolution of acute illness Vitamin D vs placebo | no estimate extracted | 3 studies · 935 participants | Low Downgraded: risk of bias, imprecision |
Duration of hospitalisation Vitamin D vs placebo | no estimate extracted | 4 studies · 835 participants | Very low Downgraded: risk of bias, imprecision |
Mortality rate Vitamin D vs placebo | RR 0.97 [0.06, 15.28] | 1 study · 193 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |