Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth
A second meta-analysis reported odds ratios of 2.44 to 3.63 favouring 38% SDF over fluoride varnish/water for caries arrest (ungraded).
2 findings from 1 review
OR (caries arrest) OR 2.44-3.63 (range); 2.44 = Chu estimate including 30% SDF
3 studies
GRADE not reported
Proportion (caries arrest) 81 [68, 89]
12 studies
GRADE not reported
Arrest of dentine caries · Children with active dentine caries in primary teeth
One study reported 30% silver diamine fluoride effectively arrested dentine caries in primary teeth; ungraded.
1 finding from 1 review
Remineralisation of early enamel caries · Children with early enamel caries in erupting permanent first molars
One pilot study found 10% silver diamine fluoride worked about as well as glass ionomer restoration and tooth-brushing for remineralising early enamel caries; ungraded.
1 finding from 1 review
Caries lesion arrestment · Primary teeth with dentin caries lesions on occlusal and smooth surfaces
Silver diamine fluoride twice annually ranked first for caries lesion arrestment in the occlusal- and smooth-surface network (moderate certainty).
1 finding from 1 review
Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)
Only one in vitro study assessed a Self-Etch adhesive with the biological ACAD protocol; it was insufficient for network meta-analysis, so no pooled effect estimate is available (ungraded).
1 finding from 1 review
Arrest of dentine caries · Children with dentine caries in primary and permanent teeth
Professionally applied 38% silver diamine fluoride arrested about two-thirds of active dentine caries surfaces in children (pooled proportion 65.9%, 95% CI 41.2% to 90.7%; 5 studies); certainty was not GRADE-rated and heterogeneity was very high (I2=96%).
1 finding from 1 review
Visual marginal discrepancy (3 years) · Patients receiving single crowns and FDPs; split-mouth
Low-gold (Midas) or silver-palladium (Albacast) alloy FDP showed no clear difference in visual marginal discrepancy (3 years) compared with high-gold content control alloy (JS C) FDP; GRADE not reported.
1 finding from 1 review
Arrest of dentine caries · Children with active dentine caries
One trial found a single application of 12% silver diamine fluoride did not arrest dentine caries; ungraded.
1 finding from 1 review
Restoration survival · Patients receiving crowns and FDPs; split-mouth, 10-year
Alternative alloy FDP (e.g., Ceramalloy II / base-metal /… led to higher restoration survival (Ceramalloy II versus Olympia) compared with high-gold content control alloy FDP (Olympia); GRADE not reported.
1 finding from 1 review
OR 3.5 [1.4, 8.7]
1 study
GRADE not reported
Laboratory cost per unit · Patients receiving crowns and FDPs; split-mouth, 10-year
1 finding from 1 review
Intervention not reported
Silver versus nonadherent · people with venous leg ulcers
The intervention probably leads to higher silver versus nonadherent (moderate certainty).
1 finding from 1 review
RR 2.43 [1.58, 3.74]
Studies not reported
Moderate
Intervention not reported
Silver versus foam · people with venous leg ulcers
The intervention may leads to higher silver versus foam (low certainty).
1 finding from 1 review
RR 2.12 [1.46, 3.07]
Studies not reported
Low
Intervention not reported
Silver versus hydrocolloid · people with venous leg ulcers
The intervention may leads to higher silver versus hydrocolloid (low certainty).
1 finding from 1 review
RR 2.32 [1.58, 3.41]
Studies not reported
Low
Intervention not reported
Sucralfate versus silver · people with venous leg ulcers
It is very uncertain whether the intervention changes sucralfate versus silver (very low certainty).
1 finding from 1 review
RR 2.8 [0.88, 8.97]
Studies not reported
Very low
Symptomatic CAUTI: without microbiological evidence ‐ silver alloy versus standard · Patients with an indwelling urethral catheter of short‐term duration
1 finding from 1 review
Symptomatic CAUTI: without microbiological evidence ‐ antibiotic versus silver alloy · Patients with an indwelling urethral catheter of short‐term duration
Antimicrobial‐impregnated catheter showed no clear difference in symptomatic CAUTI: without microbiological evidence ‐ antibiotic… compared with antiseptic‐coated catheter (moderate certainty).
1 finding from 1 review
Symptomatic CAUTI: with microbiological evidence ‐ antibiotic versus silver alloy · Patients with an indwelling urethral catheter of short‐term duration
Antimicrobial‐impregnated catheter leads to lower symptomatic CAUTI: with microbiological evidence ‐ antibiotic versus… compared with antiseptic‐coated catheter (high certainty).
1 finding from 1 review
Symptomatic CAUTI: with microbiological evidence ‐ silver alloy versus standard · Patients with an indwelling urethral catheter of short‐term duration
1 finding from 1 review
Patient discomfort whilst catheter is in situ · Patients with an indwelling urethral catheter of short‐term duration
2 findings from 1 review
Oral health-related quality of life · Children with dental caries
The direct estimate found no statistically significant difference in oral health-related quality of life between placebo and silver diamine fluoride.
2 findings from 1 review