Cochrane · systematic review · CD012583

Dressings and topical agents for treating venous leg ulcers

Norman, G, Westby, MJ, Rithalia, AD, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
10
No studies
1
Included studies
NR
No studies 1 · 9.1%Ungraded 0 · 0%Very low 3 · 27.3%Low 6 · 54.5%Moderate 1 · 9.1%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

NMA evidence: proportion with complete healing

Population: people with venous leg ulcers
11 questions
OutcomeEffectEvidenceStatus / GRADE
Contrasts
no estimate extractedNRNo studies
Sucralfate versus nonadherent
RR 6.8 [2.24, 20.7]NRLow
Downgraded: risk of bias
Sucralfate versus foam
RR 5.94 [1.96, 18]NRLow
Downgraded: risk of bias
Sucralfate versus hydrocolloid
RR 6.51 [2.17, 19.6]NRLow
Downgraded: risk of bias
Silver versus nonadherent
RR 2.43 [1.58, 3.74]NRModerate
Downgraded: risk of bias
Silver versus foam
RR 2.12 [1.46, 3.07]NRLow
Downgraded: risk of bias, imprecision, inconsistency
Silver versus hydrocolloid
RR 2.32 [1.58, 3.41]NRLow
Downgraded: risk of bias
Sucralfate versus silver
RR 2.8 [0.88, 8.97]NRVery low
Downgraded: risk of bias
Foam versus hydrocolloid
RR 1.1 [0.93, 1.28]NRVery low
Downgraded: risk of bias, imprecision, inconsistency
Foam versus nonadherent dressing
RR 1.15 [0.91, 1.44]NRLow
Downgraded: risk of bias
Hydrocolloid versus nonadherent dressing
RR 1.04 [0.85, 1.29]NRVery low
Downgraded: risk of bias