Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

696 questions · 700 findings · 53 reviews · Anaesthesia

No studies found 107 · 15.3%GRADE not reported 151 · 21.6%Very low 144 · 20.6%Low 178 · 25.4%Moderate 97 · 13.9%High 23 · 3.3%

ProSeal vs Classic laryngeal mask airway (LMA)

Inadequate oxygenation (SaO₂ < 90% on peripheral oxygen saturation) · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

It is very uncertain whether proSeal changes inadequate oxygenation (SaO₂ < 90% on peripheral oxygen saturation) compared with classic laryngeal mask airway (LMA) (very low certainty).

1 finding from 1 review

ProSeal vs Classic laryngeal mask airway (LMA)

Sore throat · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

ProSeal showed no clear difference in sore throat compared with classic laryngeal mask airway (LMA) (low certainty).

1 finding from 1 review

ProSeal vs Classic laryngeal mask airway (LMA)

Regurgitation · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

ProSeal showed no clear difference in regurgitation compared with classic laryngeal mask airway (LMA) (low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS and M‐entropy) vs standard monitoring

Awareness Postoperative interview · patients with prevention of recall of events during surgery

Anaesthesia depth monitors (BIS and M‐entropy) showed no clear difference in awareness Postoperative interview compared with standard clinical and electronic monitoring (low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS and M‐entropy) vs standard monitoring

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Awareness: definite and possible Postoperative interview · patients with prevention of recall of events during surgery

Anaesthesia depth monitors (BIS) showed no clear difference in awareness: definite and possible Postoperative interview compared with standard clinical and electronic monitoring (low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Awareness: definite Postoperative interview · patients with prevention of recall of events during surgery

Anaesthesia depth monitors (BIS) showed no clear difference in awareness: definite Postoperative interview compared with standard clinical and electronic monitoring (low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Intraoperative Wakefulness Postoperative Interview · patients with prevention of recall of events during surgery

The intervention may leads to lower intraoperative Wakefulness Postoperative Interview (low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Thiopentone and ketamine vs benzodiazepines

Awareness Postoperative interview · patients with prevention of recall of events during surgery

It is very uncertain whether thiopentone and ketamine changes awareness Postoperative interview compared with benzodiazepines (diazepam, midazolam, lorazepam) (very low certainty).

1 finding from 1 review

Thiopentone and ketamine vs benzodiazepines

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Lidocaine vs control (air/saline)

Sore throat · patients presenting with postoperative sore throat

lidocaine may leads to lower risk of sore throat 12 hours to 30 hours after the operation compared with control (air/saline) (low certainty).

2 findings from 1 review

PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation

Postoperative mortality · adult participants given general anaesthesia

It is very uncertain whether PEEP changes postoperative mortality compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation (very low certainty).

1 finding from 1 review

PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation

Pneumonia · adult participants given general anaesthesia

It is very uncertain whether PEEP changes pneumonia compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation (very low certainty).

1 finding from 1 review