Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
MRONJ (incidence proportion) · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)
1 finding from 1 review
In both study arms, no case of postoperative MRONJ was observed (700 participants; 1 RCT); effect not estimable.
1 study · 700 participants
GRADE not reported
Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
Presence of dry socket · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower dry socket compared with placebo (low certainty).
1 finding from 1 review
Infectious complications · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower postsurgical infectious complications compared with placebo (low certainty).
1 finding from 1 review
Swelling (7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes swelling (7th day) compared with placebo (very low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes pain (continuous, VAS 0-10 cm, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Pain (dichotomous, present/absent on 6th-7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes presence of pain (dichotomous, yes/no on 6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes adverse effects compared with placebo (very low certainty).
1 finding from 1 review
Trismus (dichotomous, 7th day) · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes trismus (dichotomous, 7th day) compared with placebo (very low certainty).
1 finding from 1 review
Fever · People undergoing tooth extraction (21 of 23 trials: healthy patients undergoing impacted third molar extraction; 1 routine intra-alveolar…
It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes fever (6th-7th day) compared with placebo (very low certainty).
1 finding from 1 review
Post-operative infection · Adults with fractures of the mandibular angle
Two miniplates (transbuccal approach) showed no clear difference in post-operative infection compared with one miniplate plus two screws (intraoral approach at external…; GRADE not reported.
1 finding from 1 review
Requirement for additional (surgical) interventions (plate removal) · Adults with fractures of the mandibular angle
Two miniplates (transbuccal approach) showed no clear difference in requirement for additional (surgical) interventions (plate removal) compared with one miniplate plus two screws (intraoral approach at external…; GRADE not reported.
1 finding from 1 review
RR 0.78 [0.19, 3.11]
2 studies
GRADE not reported
Post-operative adverse events and complications (lip numbness; overall) · Adults with fractures of the mandibular angle
1 finding from 1 review
Facial appearance (scar) · Adults with fractures of the mandibular angle
1 finding from 1 review
Pre-radiotherapy dental extraction vs Post-radiotherapy dental extraction
Outcome not reported · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Restoration of function (malocclusion) · Adults with fractures of the mandibular angle
Two miniplates (transbuccal approach) showed no clear difference in restoration of function (malocclusion) compared with one miniplate plus two screws (intraoral approach at external…; GRADE not reported.
1 finding from 1 review
RR 0.46 [0.05, 4.17]
1 study
GRADE not reported
Gingival index (GI) · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Persons with orofacial cleft have a higher gingival index than healthy controls (MD 0.15, 95% CI 0.11 to 0.19; low certainty).
1 finding from 1 review
Clinical attachment level (CAL) · Individuals assessed for periodontal health (mainly children and adolescents, age >2 years)
Clinical attachment level loss is greater in persons with orofacial cleft than in healthy controls (p<0.00001), but no pooled effect size was reported (ungraded).
1 finding from 1 review
Intervention not reported
Bleeding on Probing (BoP)
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported