Pre‐emptive medication vs prophylaxis
- Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes onlyno estimate extracted7 studies · 753 participantsLow
It is very uncertain whether medication reconciliation: multimodal intervention changes potential ADEs ( compared with usual care (very low certainty).
Medication reconciliation: multimodal intervention probably leads to higher discrepancy resolution ( compared with usual care (moderate certainty).
Medication reconciliation by pharmacist: database‐assisted MR may leads to lower potential ADEs ( ≥ 1 per patient) ( compared with unassisted MR (low certainty).
Medication reconciliation by pharmacist: database‐assisted MR showed no clear difference in discrepancy resolution ( compared with unassisted MR (low certainty).
Antidepressant medication may leads to lower recurrence at 12 months compared with placebo at 12 months' follow‐up (low certainty).
Antidepressant medication showed no clear difference in overall drop‐out rates (excluding deaths) at 12 months compared with placebo at 12 months' follow‐up (low certainty).
Interventions for increasing immunosuppressant medication adherence showed no clear difference in taking adherence compared with standard care (low certainty).
Interventions for increasing immunosuppressant medication adherence may leads to higher dosing adherence compared with standard care (low certainty).
Interventions for increasing immunosuppressant medication adherence showed no clear difference in timing adherence compared with standard care (low certainty).
Interventions for increasing immunosuppressant medication adherence showed no clear difference in drug holidays compared with standard care (low certainty).
It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes self‐reported adherence (proportion) compared with standard care (very low certainty).
It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes proportion of immunosuppressant trough concentration levels at target compared with standard care (very low certainty).
Varenicline probably leads to higher SAEs (varenicline vs placebo or no medication) compared with placebo or no medication (moderate certainty).
Varenicline showed no clear difference in neuropsychiatric SAEs (varenicline vs placebo or no medication) compared with placebo or no medication (low certainty).
Varenicline showed no clear difference in cardiac SAEs (varenicline vs placebo or no medication) compared with placebo or no medication (low certainty).