What do systematic reviews say?

Summary of findings: ACBT vs PEP mask therapy

• Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Very low

Summary of findings: ACBT vs PEP mask therapy

The review found no eligible studies for this question.

• Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Personal protective equipment (PPE) types: powered, air‐purifying respirator (PAPR) plus coverall vs N95 mask plus gown

It is very uncertain whether personal protective equipment (PPE) types: powered, air‐purifying… changes any contamination: fluorescent marker compared with N95 mask plus gown (very low certainty).

• Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in… 2020 · Cochrane Headline outcomes only
  RR 0.27 [0.17, 0.43]
  50 participants
  Very low

Personal protective equipment (PPE) types: powered, air‐purifying respirator (PAPR) plus coverall vs N95 mask plus gown

It is very uncertain whether personal protective equipment (PPE) types: powered, air‐purifying… changes compliance: noncompliance with donning guidance compared with N95 mask plus gown (very low certainty).

• Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in… 2020 · Cochrane Headline outcomes only
  RR 7.5 [1.81, 31.1]
  50 participants
  Very low

Personal protective equipment (PPE) types: powered, air‐purifying respirator (PAPR) plus coverall vs N95 mask plus gown

It is very uncertain whether personal protective equipment (PPE) types: powered, air‐purifying… changes compliance: noncompliance with doffing guidance compared with N95 mask plus gown (very low certainty).

• Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in… 2020 · Cochrane Headline outcomes only
  RR 0.5 [0.2, 1.23]
  50 participants
  Very low

CBT vs TRT (directive counselling and bilateral masking)

The review found no eligible studies for this question.

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

CBT vs TRT (directive counselling and bilateral masking)

CBT showed no clear difference in serious adverse effects compared with TRT (directive counselling and bilateral masking) (low certainty).

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  RR 0.45 [0.04, 4.64]
  1 study · 42 participants
  Low

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

CBT vs TRT (directive counselling and bilateral masking)

• Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

Resin infiltration vs Untreated control (natural remineralization)

Resin infiltration produced significantly greater optical improvement of white spot lesions than untreated (naturally remineralizing) controls (SMD 1.24, 95% CI 0.59 to 1.88; moderate certainty).

• Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes

  4 weeks to 6 months
  SMD 1.24 [0.59, 1.88]
  3 studies · 949 participants
  Moderate
• Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes

  4 weeks to 6 months · Visual analog scale (Senestraro et al. 2013)
  SMD 2.34 [1.68, 3.01]
  1 study · 66 participants
  GRADE not reported
• Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes

  4 weeks to 6 months · Spectroscopy delta-E (Knosel et al. 2013)
  SMD 0.63 [0.26, 1.01]
  1 study · 115 participants
  GRADE not reported

Bleaching before resin infiltration (bleaching + infiltration) vs Resin infiltration alone

Patient/dentist satisfaction did not differ between bleaching-then-infiltration and infiltration alone (SMD -1.53, 95% CI -4.75 to 1.70; ungraded).

• Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes
  SMD -1.53 [-4.75, 1.70]
  2 studies
  GRADE not reported

Resin infiltration vs Fluoride varnish

Resin infiltration produced significantly greater optical improvement than fluoride varnish (MD 4.76, 95% CI 0.74 to 8.78; moderate certainty).

• Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes

  3 to 6 months
  MD 4.76 [0.74, 8.78]
  3 studies · 212 participants
  Moderate
• Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes

  3 to 6 months · Mild lesions, DIAGNOdent score <=14 (Ciftci et al. 2018; Giray et al. 2018)
  MD 3.65 [0.82, 6.48]
  2 studies · 172 participants
  GRADE not reported
• Efficacy of resin infiltration to mask post-orthodontic or non-post-orthodontic white spot lesions or fluorosis - a… 2021 All outcomes

  3 to 6 months · Severe lesions, DIAGNOdent score >14 (Gozetici et al. 2019)
  MD 13.15 [3.98, 22.32]
  1 study · 40 participants
  GRADE not reported

LMA vs BMV

LMA probably leads to lower failure with primary modality of resuscitation compared with BMV (moderate certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.16 [0.09, 0.3]
  5 studies · 660 participants
  Moderate

LMA vs endotracheal intubation

LMA showed no clear difference in death or HIE compared with endotracheal intubation (low certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.59 [0.11, 3.32]
  1 study · 68 participants
  Low

LMA vs BMV

LMA probably leads to lower need for intubation compared with BMV (moderate certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.24 [0.12, 0.47]
  5 studies · 660 participants
  Moderate

LMA vs BMV

LMA probably leads to lower apgar score ≤ 7 at 5 minutes compared with BMV (moderate certainty).

• Laryngeal mask airway versus bag‐mask ventilation or endotracheal intubation for neonatal resuscitation 2018 · Cochrane Headline outcomes only
  RR 0.34 [0.16, 0.74]
  2 studies · 511 participants
  Moderate