Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

153 questions · 168 findings · 14 reviews · Oral and maxillofacial surgery

No studies found 61 · 36.3%GRADE not reported 58 · 34.5%Very low 29 · 17.3%Low 16 · 9.5%Moderate 4 · 2.4%High 0 · 0%

Oral diclofenac sodium (NSAID) vs splint

Pain (on movement and on palpation of the affected TMJ) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
1 finding from 1 review
  • Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
    1 week and 3 months
    Data for pain on movement or pain on palpation of the affected TMJ (both at 1 week and 3 months) could not be extracted, as they are described as percentages of an unclear total number. Narratively, diclofenac sodium…
    1 study
    GRADE not reported

Arthrocentesis and lavage vs Arthroscopy

Adverse drug reactions · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…
1 finding from 1 review
  • Only Goudot 2000 reported adverse reactions. Arthroscopy group: one transient frontal palsy (during 3 months); one cervico-facial oedema requiring prolonged intubation (12 hours). Arthrocentesis group: two severe…
    1 study · 62 participants
    GRADE not reported

Arthrocentesis and lavage vs Arthroscopy

Overall success (compound score combining pain and MIO) · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

Arthrocentesis and lavage showed no clear difference in overall success (compound score combining pain and MIO) compared with arthroscopy; GRADE not reported.

1 finding from 1 review

Arthrocentesis and lavage vs Arthroscopy

Temporomandibular joint tenderness · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

The review found no eligible studies for this question.

1 finding from 1 review

Arthrocentesis and lavage vs Arthroscopy

Deviation of the mandible · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

The review found no eligible studies for this question.

1 finding from 1 review

Arthrocentesis and lavage vs Arthroscopy

Pain (VAS) · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

Arthrocentesis and lavage showed no clear difference in pain (VAS) compared with arthroscopy; GRADE not reported.

1 finding from 1 review

Arthrocentesis and lavage vs Arthroscopy

Trismus / maximum mouth opening (mean) · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

Arthrocentesis and lavage led to lower maximum incisal (mouth) opening (MIO) compared with arthroscopy; GRADE not reported.

1 finding from 1 review

Arthrocentesis and lavage vs Arthroscopy

Improvement in pain (proportion of participants improved/healed) · Adults with temporomandibular joint disorders (internal derangement; anterior disc displacement with or without reduction) whose symptoms…

Arthrocentesis and lavage showed no clear difference in improvement in pain (proportion of participants improved/healed) compared with arthroscopy; GRADE not reported.

1 finding from 1 review

Antifibrinolytic agents (tranexamic acid (TXA) or epsilon aminocaproic acid (EACA)) vs Placebo, no intervention, or usual care

Outcome not reported · People on continuous direct oral anticoagulant (DOAC) treatment undergoing oral or dental procedures

The review found no eligible studies for this question.

1 finding from 1 review

Stabilisation splint (SS) vs Visual feedback

Movement (lateral mandibular movement) · Patients with pain dysfunction syndrome (PDS) of all degrees of severity
1 finding from 1 review

Stabilisation splint (SS) vs acupuncture

Helkimo clinical dysfunction index · Patients with pain dysfunction syndrome (PDS) of all degrees of severity
1 finding from 1 review