Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

460 questions · 464 findings · 50 reviews · Pregnancy and Childbirth

No studies found 103 · 22.2%GRADE not reported 61 · 13.1%Very low 120 · 25.9%Low 112 · 24.1%Moderate 59 · 12.7%High 9 · 1.9%

Betamethasone vs usual care

Transient tachypnoea of the neonate (TTN) · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

Effect of antenatal corticosteroids (betamethasone) showed no clear difference in transient tachypnoea of the neonate (TTN) compared with usual care prior to planned caesarean at term on maternal and… (low certainty).

1 finding from 1 review

Betamethasone vs usual care

Admission to neonatal special care (all levels) for respiratory morbidity · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

Effect of antenatal corticosteroids (betamethasone) probably leads to lower admission to neonatal special care (all levels) for respiratory… compared with usual care prior to planned caesarean at term on maternal and… (moderate certainty).

1 finding from 1 review

Betamethasone vs usual care

Need for mechanical ventilation · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

It is very uncertain whether effect of antenatal corticosteroids (betamethasone) changes need for mechanical ventilation compared with usual care prior to planned caesarean at term on maternal and… (very low certainty).

1 finding from 1 review

Metformin vs insulin

Hypertensive disorders of pregnancy: pre‐eclampsia · women with type 2 diabetes

It is very uncertain whether maternal outcomes: oral anti‐diabetic agent (metformin) changes hypertensive disorders of pregnancy: pre‐eclampsia compared with insulin (very low certainty).

1 finding from 1 review

Metformin vs insulin

Hypertensive disorders of pregnancy (pregnancy‐induced hypertension) · women with type 2 diabetes

Maternal outcomes: oral anti‐diabetic agent (metformin) may leads to lower hypertensive disorders of pregnancy: pregnancy‐induced hypertension compared with insulin (low certainty).

1 finding from 1 review