Metformin vs insulin: Induction of labour
- Population
- women with type 2 diabetes
- Intervention
- Metformin
- Comparison
- insulin
- Outcome
- Induction of labour
It is very uncertain whether maternal outcomes: oral anti‐diabetic agent (metformin) changes induction of labour compared with insulin (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Maternal outcomes: oral anti‐diabetic agent (metformin) vs insulin Induction of labour · women with type 2 diabetes It is very uncertain whether maternal outcomes: oral anti‐diabetic agent (metformin) changes induction of labour compared with insulin (very low certainty). Oral anti‐diabetic agents for women with established diabetes/impaired glucose tolerance or previous… (2017) · Cochrane Headline outcomes only | RR 1.42 [0.62, 3.28] | 2 studies · 35 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral anti‐diabetic agents for women with established diabetes/impaired glucose tolerance or previous gestational diabetes planning… 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Metformin vs glibenclamide ‐ maternal outcomes · women with gestational diabetes mellitus · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.