Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

451 questions · 479 findings · 42 reviews · Stroke

No studies found 147 · 30.7%GRADE not reported 22 · 4.6%Very low 130 · 27.1%Low 103 · 21.5%Moderate 60 · 12.5%High 17 · 3.5%

Body awareness interventions vs control

Neglect outcomes: immediate effects · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes neglect outcomes: immediate effects compared with any control (very low certainty).

1 finding from 1 review

Body awareness interventions vs control

Adverse events · spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury

It is very uncertain whether body awareness interventions changes adverse events compared with any control (very low certainty).

1 finding from 1 review

Organisational interventions vs usual care

Blood pressure target achievement · The trials included a total of 33,840 participants with cerebrovascular disease. The mean or median age of participants ranged from 60…

Organisational interventions probably leads to higher blood pressure target achievement compared with usual care (moderate certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: meeting study criteria for depression at end of… compared with placebo (very low certainty).

2 findings from 1 review

Pharmacological interventions vs placebo

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: < 50% reduction in scale scores at end of treatment… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Adverse events: death ‐ at end of treatment (secondary outcome) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: death (secondary outcome) compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Adverse effects (central nervous system) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: all ‐ central nervous system events (e.g. confusion,… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Gastrointestinal adverse events · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: all ‐ gastrointestinal effects (e.g. constipation,… compared with placebo (very low certainty).

1 finding from 1 review