What do systematic reviews say?

Silicone oil vs perfluropropane (C3F8)

Silicone oil showed no clear difference in visual acuity ≥ 5/200 at 3 years compared with perfluropropane (C3F8) (low certainty).

• Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy 2020 · Cochrane Headline outcomes only
  RR 0.97 [0.73, 1.31]
  1 study · 264 participants
  Low

Silicone oil vs perfluropropane (C3F8)

Silicone oil showed no clear difference in macular attachment at 3 years compared with perfluropropane (C3F8) (low certainty).

• Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy 2020 · Cochrane Headline outcomes only
  RR 1 [0.86, 1.15]
  1 study · 264 participants
  Low

Single herb plus conventional intervention vs conventional intervention

Single herb plus conventional intervention may leads to higher visual acuity (gain of ≥ 2 lines) (end of treatment) compared with conventional intervention (low certainty).

• Single herbal medicine for diabetic retinopathy 2018 · Cochrane Headline outcomes only
  RR 1.26 [1.08, 1.48]
  5 studies · 541 participants
  Low

Single herb plus conventional intervention vs conventional intervention

It is very uncertain whether single herb plus conventional intervention changes reduction in microaneurysms compared with conventional intervention (very low certainty).

• Single herbal medicine for diabetic retinopathy 2018 · Cochrane Headline outcomes only
  RR 17.9 [1.05, 305.26]
  1 study · 146 participants
  Very low

Single herb plus conventional intervention vs conventional intervention

It is very uncertain whether single herb plus conventional intervention changes observations in retina: reduction in haemorrhages compared with conventional intervention (very low certainty).

• Single herbal medicine for diabetic retinopathy 2018 · Cochrane Headline outcomes only
  RR 26.3 [1.59, 437.56]
  1 study · 146 participants
  Very low

Single herb plus conventional intervention vs conventional intervention

• Single herbal medicine for diabetic retinopathy 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 215 participants
  Low

Single herb plus conventional intervention vs conventional intervention

• Single herbal medicine for diabetic retinopathy 2018 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 687 participants
  Very low

Any quality improvement intervention vs usual care

• Interventions to increase attendance for diabetic retinopathy screening 2018 · Cochrane Headline outcomes only
  no estimate extracted
  56 studies · 329164 participants
  Low

Any quality improvement intervention vs usual care

The review found no eligible studies for this question.

• Interventions to increase attendance for diabetic retinopathy screening 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Any quality improvement intervention vs usual care

• Interventions to increase attendance for diabetic retinopathy screening 2018 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 85 participants
  Low

Any quality improvement intervention vs usual care

• Interventions to increase attendance for diabetic retinopathy screening 2018 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 85 participants
  Low

Any quality improvement intervention vs usual care

• Interventions to increase attendance for diabetic retinopathy screening 2018 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 85 participants
  Low

Stepped quality improvement intervention vs the intervention alone

• Interventions to increase attendance for diabetic retinopathy screening 2018 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 23715 participants
  Moderate

Stepped quality improvement intervention vs the intervention alone

The review found no eligible studies for this question.

• Interventions to increase attendance for diabetic retinopathy screening 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Stepped quality improvement intervention vs the intervention alone

The review found no eligible studies for this question.

• Interventions to increase attendance for diabetic retinopathy screening 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Nd:YAG laser vs argon‐green laser

It is very uncertain whether nd:YAG laser changes BCVA: loss of 15 or more ETDRS letters compared with argon‐green laser (very low certainty).

• Different lasers and techniques for proliferative diabetic retinopathy 2018 · Cochrane Headline outcomes only
  RR 0.8 [0.3, 2.13]
  1 study · 20 participants
  Very low

Diode laser vs argon laser

It is very uncertain whether diode laser changes progression of PDR compared with argon laser (very low certainty).

• Different lasers and techniques for proliferative diabetic retinopathy 2018 · Cochrane Headline outcomes only
  RR 0.9 [0.41, 2]
  1 study · 66 participants
  Very low

Diode laser vs argon laser

It is very uncertain whether diode laser changes regression of PDR compared with argon laser (very low certainty).

• Different lasers and techniques for proliferative diabetic retinopathy 2018 · Cochrane Headline outcomes only
  RR 0.75 [0.35, 1.6]
  1 study · 66 participants
  Very low

Diode laser vs argon laser

Diode laser probably leads to higher pain during laser treatment compared with argon laser (moderate certainty).

• Different lasers and techniques for proliferative diabetic retinopathy 2018 · Cochrane Headline outcomes only
  RR 3.07 [2.15, 4.39]
  4 studies · 228 participants
  Moderate

Diode laser vs argon laser

The review found no eligible studies for this question.

• Different lasers and techniques for proliferative diabetic retinopathy 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found