Number experiencing adverse effects · children with cystic fibrosis and a new culture positive for P aeruginosa
Inhaled tobramycin (TNS) plus oral azithromycin showed no clear difference in adverse effects of antibiotics: number of participants experiencing… compared with TNS plus oral placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Mean FEV1 % predicted ‐ azithromycin prophylaxis only · children with cystic fibrosis aged 12 years and under
1 finding from 1 review
Intervention not reported
Episodes of pulmonary exacerbations ‐ azithromycin prophylaxis only · children with cystic fibrosis aged 12 years and under
The intervention leads to lower episodes of pulmonary exacerbations ‐ azithromycin prophylaxis only (high certainty).
1 finding from 1 review
Relapse · children under 18 years of age with enteric fever
It is very uncertain whether ceftriaxone changes relapse compared with azithromycin (very low certainty).
1 finding from 1 review
Time to defervescence · children under 18 years of age with enteric fever
Ceftriaxone showed no clear difference in time to defervescence compared with azithromycin (low certainty).
1 finding from 1 review
Length of hospital stay · children under 18 years of age with enteric fever
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Convalescent faecal carriage · children under 18 years of age with enteric fever
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · children under 18 years of age with enteric fever
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical failure · children under 18 years of age with enteric fever
Ceftriaxone showed no clear difference in clinical failure compared with azithromycin (low certainty).
1 finding from 1 review
Microbiological failure · children under 18 years of age with enteric fever
It is very uncertain whether ceftriaxone changes microbiological failure compared with azithromycin (very low certainty).
1 finding from 1 review
Microbiological cure · Pregnant women with a confirmed Chlamydia trachomatis infection
It is very uncertain whether amoxicillin changes microbiological cure compared with azithromycin (very low certainty).
1 finding from 1 review