Intervention not reported
- Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 38 participantsModerate
Oral or topical or intraperitoneal antibiotics showed no clear difference in peritonitis (number of patients with one or more episodes) compared with placebo/no treatment (low certainty).
Antifungal may leads to lower fungal peritonitis (number of patients with one or more episodes) compared with placebo/no treatment (low certainty).
Oral or topical or intraperitoneal antibiotics showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with placebo/no treatment (low certainty).
Oral or topical or intraperitoneal antibiotics showed no clear difference in catheter removal or replacement (number of patients) compared with placebo/no treatment (low certainty).
Nasal antibiotics showed no clear difference in peritonitis (number of patients with one or more episodes) compared with placebo/no treatment (low certainty).
Nasal antibiotics showed no clear difference in exit‐site/ tunnel infection (number of patients with one or more… compared with placebo/no treatment (low certainty).
Nasal antibiotics showed no clear difference in catheter removal or replacement (number of patients) compared with placebo/no treatment (low certainty).
Topical disinfectants showed no clear difference in peritonitis (number of patients with one or more episodes) compared with standard care or other active treatment (antibiotic or other… (low certainty).
Topical disinfectants showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with standard care or other active treatment (antibiotic or other… (low certainty).
Topical disinfectants showed no clear difference in catheter removal or replacement (number of patients) compared with standard care or other active treatment (antibiotic or other… (low certainty).
Chlorhexidine dressing following alcohol cleansing showed no clear difference in sepsis without a source compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).
Chlorhexidine dressing following alcohol cleansing showed no clear difference in catheter‐related blood stream infection compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).
Chlorhexidine dressing following alcohol cleansing probably leads to lower catheter colonisation compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).
Chlorhexidine dressing following alcohol cleansing probably leads to higher adverse effects: contact dermatitis compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).
Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods compared with control (moderate certainty).
Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: catheters Clinial and microbiological… compared with control (moderate certainty).
Silver‐alginate dressing showed no clear difference in mortality Clinial assessment compared with control (moderate certainty).
Antibiotic leads to lower surgical wound infection (SWI) compared with no antibiotic/placebo (high certainty).