Cochrane · systematic review · CD011082
Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous catheters
Lai, NM, Taylor, JE, Tan, K, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 12.5%Very low 0 · 0%Low 0 · 0%Moderate 7 · 87.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Chlorhexidine dressing following alcohol cleansing compared to polyurethane dressing following aqueous povidone‐iodine cleansing for the prevention of catheter‐related infections in newborn infants with central venous catheters
Population: newborn infants with central venous catheters
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Sepsis without a source Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing | RR 1.06 [0.75, 1.52] | 1 study · 705 participants | Moderate Downgraded: imprecision |
Catheter‐related blood stream infection Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing | RR 1.18 [0.53, 2.65] | 1 study · 655 participants | Moderate Downgraded: imprecision |
Catheter colonisation Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing | RR 0.62 [0.45, 0.86] | 1 study · 655 participants | Moderate Downgraded: imprecision |
Adverse effects: contact dermatitis Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing | RR 43.06 [2.61, 710.44] | 1 study · 670 participants | Moderate Downgraded: imprecision |
Silver‐alginate dressing versus control for the prevention of catheter‐related infections in newborn infants with central venous catheters
Population: newborn infants with central venous catheters
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods Silver‐alginate dressing vs control | RR 0.5 [0.14, 1.78] | 1 study · 50 participants | Moderate |
CRBSI ‐ Unit of analysis: catheters Clinial and microbiological methods Silver‐alginate dressing vs control | RR 0.72 [0.27, 1.89] | 1 study · 118 participants | Moderate |
Mortality Clinial assessment Silver‐alginate dressing vs control | RR 0.55 [0.15, 2.05] | 2 studies · 150 participants | Moderate |
Adverse effects: contact dermatitis Silver‐alginate dressing vs control | no estimate extracted | 2 studies · 150 participants | Ungraded |