Findings

What do systematic reviews say?

127 questions · 128 findings · 15 reviews · Pregnancy and Childbirth

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No studies found 19 · 14.8%GRADE not reported 35 · 27.3%Very low 25 · 19.5%Low 29 · 22.7%Moderate 12 · 9.4%High 8 · 6.3%

Antibiotics vs placebo or no antibiotic

Neonatal mortality · pregnant women with prelabour rupture of membranes at or near term

1 finding from 1 review

Antibiotics for prelabour rupture of membranes at or near term 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1906 participants
GRADE not reported

Antibiotics vs placebo

Neonatal sepsis · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

Antibiotic showed no clear difference in neonatal sepsis compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
RR 1 [0.21, 4.76]
1 study · 120 participants
Low

Antibiotics vs placebo

Chorioamnionitis · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

Antibiotic probably leads to lower chorioamnionitis compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
RR 0.36 [0.21, 0.62]
2 studies · 362 participants
Moderate

Antibiotics vs placebo

Postpartum endometritis · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

Antibiotic showed no clear difference in postpartum endometritis compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
RR 0.5 [0.18, 1.38]
1 study · 120 participants
Low

Antibiotics vs placebo

Mortality and morbidity prior to discharge (Neonatal intensive care admissions) · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

Antibiotic showed no clear difference in mortality and morbidity prior to discharge (Neonatal intensive care… compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
RR 0.83 [0.39, 1.78]
1 study · 120 participants
Low

Antibiotics vs placebo

Side effects · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo

Duration of admission to neonatal intensive care unit · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found