Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

144 questions · 145 findings · 16 reviews · Eyes and Vision

No studies found 46 · 31.7%GRADE not reported 0 · 0%Very low 30 · 20.7%Low 21 · 14.5%Moderate 44 · 30.3%High 4 · 2.8%

Microcatheter‐assisted trabeculotomy vs conventional trabeculotomy

Proportion of participants with IOP≤ 21 mmHg, with or without ocular hypotensive medications 1 year · children at or before five years of age with primary congenital glaucoma

Microcatheter‐assisted trabeculotomy probably leads to higher proportion with postoperative IOP ≤ 21 mmHg (surgical success) with… compared with conventional trabeculotomy (moderate certainty).

1 finding from 1 review

Microcatheter‐assisted trabeculotomy vs conventional trabeculotomy

Hyphema · children at or before five years of age with primary congenital glaucoma

Microcatheter‐assisted trabeculotomy probably leads to higher adverse outcomes— hyphema Up to 1 year after surgery compared with conventional trabeculotomy (moderate certainty).

1 finding from 1 review

Intervention not reported

Uncorrected visual acuity (UCVA) of 20/20 or better · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

It is very uncertain whether the intervention changes uncorrected visual acuity (UCVA) of 20/20 or better (very low certainty).

1 finding from 1 review

Intervention not reported

Uncorrected visual acuity (UCVA) of 20/40 or better · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

It is very uncertain whether the intervention changes uncorrected visual acuity (UCVA) of 20/40 or better (very low certainty).

1 finding from 1 review

Intervention not reported

Proportion of participants who lost two or more lines of best‐corrected visual acuity (BCVA) · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Eyes within ± 0.5 D of target refraction · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

It is very uncertain whether the intervention changes eyes within ± 0.5 D of target refraction (very low certainty).

1 finding from 1 review

Intervention not reported

Reported complications Laser capsulotomies for posterior capsule opacification (PCO) · Participants over age of 21 years undergoing cataract surgery

The intervention may leads to higher reported complications Laser capsulotomies for posterior capsule… (low certainty).

1 finding from 1 review

Binocular iPad treatment vs occlusion therapy

Visual acuity · 5‐ to 8‐year‐old children with amblyopia
2 findings from 1 review