Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

677 questions · 719 findings · 133 reviews

No studies found 153 · 21.3%GRADE not reported 54 · 7.5%Very low 164 · 22.8%Low 199 · 27.7%Moderate 119 · 16.6%High 30 · 4.2%

Macrolides vs tetracycline

Quality of life Drug resistance/microbial sensitivity Serious adverse events Lung function Hospitalisations Adverse events/side effects Number of participants colonised with P aeruginosa · patients with chronic obstructive pulmonary disease

The review found no eligible studies for this question.

1 finding from 1 review

Tacrolimus vs cyclosporin

Complete or partial remission · idiopathic steroid‐resistant nephrotic syndrome in children

Tacrolimus showed no clear difference in treatment response at 6 months: complete and partial remission compared with cyclosporin (low certainty).

2 findings from 1 review