Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,520 questions · 1,575 findings · 175 reviews · Headline outcomes only

No studies found 239 · 15.2%GRADE not reported 59 · 3.7%Very low 337 · 21.4%Low 406 · 25.8%Moderate 410 · 26%High 124 · 7.9%

Intervention not reported

Mortality · acute bacterial meningitis

The intervention showed no clear difference in mortality (moderate certainty).

1 finding from 1 review

Intervention not reported

Severe hearing loss · acute bacterial meningitis

The intervention leads to lower severe hearing loss (high certainty).

1 finding from 1 review

Intervention not reported

Any hearing loss · acute bacterial meningitis

The intervention leads to lower any hearing loss (high certainty).

1 finding from 1 review

Intervention not reported

Short‐term neurological sequelae · acute bacterial meningitis

The intervention showed no clear difference in short‐term neurological sequelae (high certainty).

1 finding from 1 review

Intervention not reported

Adverse events ‐ recurrent fever · acute bacterial meningitis

The intervention probably leads to higher adverse events ‐ recurrent fever (moderate certainty).

1 finding from 1 review