Cochrane · systematic review · CD004405
Corticosteroids for acute bacterial meningitis
Brouwer, MC, McIntyre, P, Prasad, K, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 40%High 3 · 60%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table
Population: acute bacterial meningitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality | RR 0.9 [0.8, 1.01] | 25 studies · 4121 participants | Moderate |
Severe hearing loss | RR 0.67 [0.51, 0.88] | 17 studies · 2437 participants | High |
Any hearing loss | RR 0.74 [0.63, 0.87] | 20 studies · 2785 participants | High |
Short‐term neurological sequelae | RR 0.83 [0.69, 1] | 13 studies · 1756 participants | High |
Adverse events ‐ recurrent fever | RR 1.27 [1.09, 1.47] | 12 studies · 1723 participants | Moderate Downgraded: imprecision |