Findings

What do systematic reviews say?

4,760 questions · 8,065 findings · 1,036 reviews

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No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Maintenance treatment with antipsychotic drugs vs placebo/no treatment

Social functioning · schizophrenia

1 finding from 1 review

Maintenance treatment with antipsychotic drugs for schizophrenia 2020 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 3588 participants
Moderate

Intervention not reported

Foot alignmentPirani score. Scale from: 0 to 6. A lower score indicates better alignment · participants with CTEV at initial presentation

1 finding from 1 review

Interventions for congenital talipes equinovarus (clubfoot) 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Intervention not reported

Foot alignment Pirani score. A lower score indicates better alignment. Scale from: 0 to 6. · participants with CTEV (type of case (i.e. whether initial presentation or relapsed) not specified)

1 finding from 1 review

Interventions for congenital talipes equinovarus (clubfoot) 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

Anaemia · children aged 6 to 23 months

Home (point‐of‐use) fortification of foods with multiple… probably leads to lower anaemia (haemoglobin values lower than 110 g/L) compared with no intervention or placebo (moderate certainty).

1 finding from 1 review

Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years… 2020 · Cochrane Headline outcomes only
RR 0.82 [0.76, 0.9]
16 studies · 9927 participants
Moderate

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement

Anaemia · children aged 6 to 23 months

Home (point‐of‐use) fortification of foods with multiple… showed no clear difference in anaemia (haemoglobin values lower than 110 g/L) compared with an iron‐only supplement (low certainty).

1 finding from 1 review

Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years… 2020 · Cochrane Headline outcomes only
RR 0.89 [0.58, 1.39]
1 study · 145 participants
Low

Oral progestogen (dienogest, desogestrel) vs goserelin acetate

Uterine fibroid‐related symptoms (duration of uterine bleeding, measured at 12 weeks; lower = better) · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Oral progestogen (dienogest, desogestrel) vs goserelin acetate

Uterine fibroid‐related symptoms (abnormal uterine bleeding, measured at 12 weeks, with the pictorial blood assessment chart (PBAC); lower = better) · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

LNG‐IUS vs oral progestogen (norethisterone acetate)

Change in fibroid related symptoms · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Very low

Acupuncture vs no treatment

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 163 participants
Very low

Acupressure vs sham control

Pain intensity (0‐10cm visual analogue scale) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 472 participants
Very low

Acupressure vs usual care

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 620 participants
Very low

Anti‐VEGF vs steroids

Central retinal thickness μm (CRT) change at 1 year The aim of treatment is to reduce central retinal thickness so thinner is better. · people with BRVO

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 343 participants
Moderate

Anti‐VEGF vs sham

Mean central retinal thickness (CRT) change at 6 months in microns (lower value is better) · macular oedema secondary to branch retinal vein occlusion

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 281 participants
Moderate

Anti‐VEGF vs laser

Mean central retinal thickness (CRT) change at 6 months in microns (lower value is better) · people with BRVO

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 201 participants
Moderate

tDCS vs active control

Secondary outcome measure: lower extremity function at the end of · people with stroke

2 findings from 1 review

Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 66 participants
Moderate
Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

tDCS vs placebo or control

Secondary outcome measure: lower extremity function at the end of · people with stroke

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 204 participants
Moderate

Intervention not reported

PIPP (maximum score within 3 minutes following lancing) · Neonates

1 finding from 1 review

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Intervention not reported

Stratum corneum hydration (SCH) (at baseline and day 56 ± 4) Hahnel 2017: measured at 56 ± 4 days in mid‐volar arm and lower leg in arbitrary units from 0 (no water) to 120 (on water) using the Corneometer CM 825 Gillis 2016: measured at 12 weeks ... · people 60 years of age and older

1 finding from 1 review

Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 266 participants
Very low

Simulation‐based obstetric team training vs no training

Low Apgar score

Simulation‐based obstetric team training showed no clear difference in low Apgar score (Kirkpatrick level 4: patient outcome) compared with no training (low certainty).

1 finding from 1 review

Multi‐professional simulation‐based team training in obstetric emergencies for improving patient outcomes and… 2020 · Cochrane Headline outcomes only
RR 0.99 [0.85, 1.15]
2 studies · 115171 participants
Low

rHuEPO with iron vs control treatment with or without iron

Subgroup Hb concentration immediately prior to surgery (g/dL) rHuEPO low (150 to 300 IU/kg BW) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia

1 finding from 1 review

Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing… 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 334 participants
Low